Literature DB >> 27419815

Trichomonas vaginalis Nucleic Acid Amplification Testing at an Urban HIV Clinic.

Christina A Muzny1, Greer A Burkholder, Karen R Fry, Erika L Austin, Jane R Schwebke.   

Abstract

BACKGROUND: Trichomonas vaginalis is the most common nonviral sexually transmitted infection. T. vaginalis nucleic acid amplification testing (NAAT) recently became available at the University of Alabama at Birmingham human immunodeficiency virus (HIV) clinic. The objective of this study was to determine the uptake of T. vaginalis NAAT testing among clinic providers during the first year of test availability in addition to T. vaginalis prevalence and predictors based on NAAT results.
METHODS: This was a retrospective review of HIV+ women and men ages ≥16 years at the University of Alabama at Birmingham HIV Clinic, including those receiving a T. vaginalis NAAT on a genitourinary specimen.
RESULTS: Between August 2014 and August 2015, 3163 HIV+ patients were seen (768 women, 2395 men), of whom 861 (27.3%) received a T. vaginalis NAAT; 402 women (52.3%) and 459 men (19.2%). Among those with T. vaginalis NAAT results, 70 (17.4%) of 402 women and 12 (2.6%) of 459 men (9 men who have sex with women, 1 man who has sex with men, 2 unknown) tested positive. In adjusted analyses for women, age ≤40 years (odds ratio [OR], 2.93; 95% confidence interval [CI], 1.23-6.96), current cocaine use (OR, 4.86; 95% CI, 1.57-15.06), and CD4 < 200 cells/mm (OR, 6.09; 95% CI, 1.68-22.11) were significantly associated with increased odds of a positive T. vaginalis NAAT. For those with a positive T. vaginalis NAAT, treatment was prescribed for 65 (92.9%) of 70 women and 10 (83.3%) of 12 men.
CONCLUSIONS: Initial uptake of T. vaginalis NAAT testing was modest at this HIV clinic yet identified a high prevalence among women tested. Emphasis on the need for testing in HIV+ women is necessary.

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Mesh:

Year:  2016        PMID: 27419815     DOI: 10.1097/OLQ.0000000000000479

Source DB:  PubMed          Journal:  Sex Transm Dis        ISSN: 0148-5717            Impact factor:   2.830


  8 in total

1.  Why Does Trichomonas vaginalis Continue to be a "Neglected" Sexually Transmitted Infection?

Authors:  Christina A Muzny
Journal:  Clin Infect Dis       Date:  2018-07-02       Impact factor: 9.079

2.  Budgetary Impact of Compliance With STI Screening Guidelines in Persons Living With HIV.

Authors:  Ellen F Eaton; Kathryn Hudak; Christina A Muzny
Journal:  J Acquir Immune Defic Syndr       Date:  2017-03-01       Impact factor: 3.731

3.  Prevalence and Correlates of Trichomonas vaginalis Infection Among Men and Women in the United States.

Authors:  Eshan U Patel; Charlotte A Gaydos; Zoe R Packman; Thomas C Quinn; Aaron A R Tobian
Journal:  Clin Infect Dis       Date:  2018-07-02       Impact factor: 9.079

4.  Sexually Transmitted Infection Prevalence in Women With HIV: Is There a Role for Targeted Screening?

Authors:  Jodie Dionne-Odom; Andrew O Westfall; Barbara Van Der Pol; Karen Fry; Jeanne Marrazzo
Journal:  Sex Transm Dis       Date:  2018-11       Impact factor: 2.830

5.  Development of a convenient detection method for Trichomonas vaginalis based on loop-mediated isothermal amplification targeting adhesion protein 65.

Authors:  Yuhua Li; Shuai Wang; Haoran Li; Xiaoxiao Song; Hao Zhang; Yujuan Duan; Chengyang Luo; Bingli Wang; Sifan Ji; Qing Xie; Zhenchao Zhang
Journal:  BMC Infect Dis       Date:  2020-05-01       Impact factor: 3.090

Review 6.  Epidemiology, Natural History, Diagnosis, and Treatment of Trichomonas vaginalis in Men.

Authors:  Olivia T Van Gerwen; Andres F Camino; Jyoti Sharma; Patricia J Kissinger; Christina A Muzny
Journal:  Clin Infect Dis       Date:  2021-09-15       Impact factor: 20.999

7.  Trichomonas vaginalis infection and the diagnostic significance of detection tests among Ghanaian outpatients.

Authors:  Richard Harry Asmah; Rita Ofosuaa Agyeman; Noah Obeng-Nkrumah; Harriet Blankson; Georgina Awuah-Mensah; Momodou Cham; Listowell Asare; Patrick Ferdinand Ayeh-Kumi
Journal:  BMC Womens Health       Date:  2018-12-27       Impact factor: 2.809

Review 8.  Recent advances in the epidemiology, diagnosis, and management of Trichomonas vaginalis infection.

Authors:  Olivia T Van Gerwen; Christina A Muzny
Journal:  F1000Res       Date:  2019-09-20
  8 in total

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