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Literature DB >> 27418575

Zika Virus Infection Associated With Severe Thrombocytopenia.

Tyler M Sharp¹, Jorge Muñoz-Jordán¹, Janice Perez-Padilla¹, Melissa I Bello-Pagán², Aidsa Rivera¹, Daniel M Pastula³, Jorge L Salinas⁴, Jose H Martínez Mendez⁵, Mónica Méndez⁶, Ann M Powers⁷, Stephen Waterman¹, Brenda Rivera-García².

Abstract

We report two patients that developed severe thrombocytopenia after Zika virus (ZIKV) infection. The first patient had 1000 platelets/μL and died after multiple hemorrhages. The second patient had 2000 platelets/μL, had melena and ecchymoses, and recovered after receiving intravenous immunoglobulin. ZIKV may be associated with immune-mediated severe thrombocytopenia. Published by Oxford University Press for the Infectious Diseases Society of America 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Entities: Chemical Disease Gene Species

Keywords: Puerto Rico; Zika virus; fatal; thrombocytopenia

Mesh：

Substances：

Year: 2016 PMID： 27418575 PMCID： PMC5176332 DOI： 10.1093/cid/ciw476

Source DB: PubMed Journal: Clin Infect Dis ISSN： 1058-4838 Impact factor: 9.079

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