Literature DB >> 27418554

Continuous laryngoscopy quantitates laryngeal behaviour in exercise and recovery.

J Tod Olin1, Matthew S Clary2, Elizabeth M Fan3, Kristina L Johnston4, Claire M State3, Matthew Strand5, Kent L Christopher6.   

Abstract

Exercise-induced laryngeal obstruction (E-ILO) causes exertional dyspnoea. There is no standardised methodology which characterises laryngeal obstruction in relation to exercise or links laryngeal obstruction and dyspnoea severity. Continuous laryngoscopy during exercise (CLE) may improve diagnostic sensitivity by enabling laryngeal visualisation at peak work capacity in patients with rapidly resolving obstruction. The time course of laryngeal obstruction across exercise and recovery has not been quantitated until this report.Adolescents and young adults referred for CLE were laryngoscopically monitored across rest, maximal cycle ergometry exercise, and recovery. Three reviewers, blinded to time sequencing, rated inspiratory glottic and supraglottic obstruction during 10 windows of 15-s corresponding to rest, 25%, 50%, 75%, 90% and 100% of individual symptom-limited peak work capacity (expressed in Watts), and four consecutive recovery windows.85 patients were screened and 71 included. Over 96% of time windows were interpretable. Laryngeal obstruction severity reached observed maximal levels at peak work capacity, and rapidly resolved. A spectrum of observed maximal obstruction was measured.CLE provides interpretable data demonstrating laryngeal obstruction in patients with suspected E-ILO that is more severe at peak work capacity than during rest, submaximal exercise, or recovery. Observed maximal obstruction was infrequently severe and rapidly resolved.
Copyright ©ERS 2016.

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Mesh:

Year:  2016        PMID: 27418554     DOI: 10.1183/13993003.00160-2016

Source DB:  PubMed          Journal:  Eur Respir J        ISSN: 0903-1936            Impact factor:   16.671


  12 in total

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Authors:  Jerome A Dempsey; Andre La Gerche; James H Hull
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2.  Heredity of supraglottic exercise-induced laryngeal obstruction.

Authors:  Emil Schwarz Walsted; Jeppe Hvedstrup; Hans Eiberg; Vibeke Backer
Journal:  Eur Respir J       Date:  2017-08-17       Impact factor: 16.671

3.  Increased respiratory neural drive and work of breathing in exercise-induced laryngeal obstruction.

Authors:  Emil S Walsted; Azmy Faisal; Caroline J Jolley; Laura L Swanton; Matthew J Pavitt; Yuan-Ming Luo; Vibeke Backer; Michael I Polkey; James H Hull
Journal:  J Appl Physiol (1985)       Date:  2017-11-02

4.  The Role of Comorbidities in Difficult-to-Control Asthma in Adults and Children.

Authors:  Jonathan M Gaffin; Mario Castro; Leonard B Bacharier; Anne L Fuhlbrigge
Journal:  J Allergy Clin Immunol Pract       Date:  2021-12-01

Review 5.  Pathophysiology and clinical evaluation of the patient with unexplained persistent dyspnea.

Authors:  Andi Hudler; Fernando Holguin; Meghan Althoff; Anne Fuhlbrigge; Sunita Sharma
Journal:  Expert Rev Respir Med       Date:  2022-01-20       Impact factor: 4.300

Review 6.  A systematic review of surgical treatment for supraglottic exercise-induced laryngeal obstruction.

Authors:  Karina Siewers; Vibeke Backer; Emil Schwarz Walsted
Journal:  Laryngoscope Investig Otolaryngol       Date:  2019-03-06

7.  Characteristics and impact of exercise-induced laryngeal obstruction: an international perspective.

Authors:  Emil S Walsted; Bamidele Famokunwa; Louise Andersen; Sune L Rubak; Frederik Buchvald; Lars Pedersen; James Dodd; Vibeke Backer; Kim G Nielsen; Andrew Getzin; James H Hull
Journal:  ERJ Open Res       Date:  2021-06-28

8.  Validity and reliability of grade scoring in the diagnosis of exercise-induced laryngeal obstruction.

Authors:  Emil Schwarz Walsted; James H Hull; Jeppe Hvedstrup; Robert Christiaan Maat; Vibeke Backer
Journal:  ERJ Open Res       Date:  2017-07-28

9.  Observational study of laryngoscopy plus flow-volume loops during exercise.

Authors:  Paolo T Pianosi; Diana M Orbelo; Shelagh A Cofer
Journal:  Clin Case Rep       Date:  2018-03-04

10.  Exercise-induced laryngeal obstruction in athletes treated with inspiratory muscle training.

Authors:  Astrid Sandnes; Tiina Andersen; Hege Havstad Clemm; Magnus Hilland; Maria Vollsæter; John-Helge Heimdal; Geir Egil Eide; Thomas Halvorsen; Ola Drange Røksund
Journal:  BMJ Open Sport Exerc Med       Date:  2019-01-18
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