Literature DB >> 27417955

WT1 Mutation in Childhood Cancer.

Jocelyn Charlton1, Kathy Pritchard-Jones2,3.   

Abstract

In this chapter, the role of WT1 in childhood cancer is discussed, using the key examples Wilms' tumor, desmoplastic small round cell of childhood, and leukemia. The role of WT1 in each disease is described and mirrored to the role of WT1 in normal development.

Entities:  

Keywords:  Childhood cancer; Desmoplastic small round cell tumor of childhood; Development; Leukemia; Minimal residual disease; Wilms’ tumor

Mesh：

Substances：

Year:  2016        PMID： 27417955     DOI： 10.1007/978-1-4939-4023-3_1

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  5 in total

1.  Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis.

Authors:  Elodie Pronier; Robert L Bowman; Jihae Ahn; Jacob Glass; Cyriac Kandoth; Tiffany R Merlinsky; Justin T Whitfield; Benjamin H Durham; Antoine Gruet; Amritha Varshini Hanasoge Somasundara; Raajit Rampal; Ari Melnick; Richard P Koche; Barry S Taylor; Ross L Levine
Journal:  Blood       Date:  2018-07-31       Impact factor: 22.113

2.  Polymorphisms in the Wilms Tumor Gene Are Associated With Interindividual Variations in Rubella Virus-Specific Cellular Immunity After Measles-Mumps-Rubella II Vaccination.

Authors:  Emily A Voigt; Iana H Haralambieva; Beth L Larrabee; Richard B Kennedy; Inna G Ovsyannikova; Daniel J Schaid; Gregory A Poland
Journal:  J Infect Dis       Date:  2018-01-30       Impact factor: 5.226

3.  Evaluating Established Roles, Future Perspectives and Methodological Heterogeneity for Wilms' Tumor 1 (WT1) Antigen Detection in Adult Renal Cell Carcinoma, Using a Novel N-Terminus Targeted Antibody (Clone WT49).

Authors:  Dorin Novacescu; Talida Georgiana Cut; Alin Adrian Cumpanas; Silviu Constantin Latcu; Razvan Bardan; Ovidiu Ferician; Cosmin-Ciprian Secasan; Andrei Rusmir; Marius Raica
Journal:  Biomedicines       Date:  2022-04-15

4.  Bioinformatics analysis and identification of genes and pathways involved in patients with Wilms tumor.

Authors:  Yufeng Li; Haizhou Tang; Zhenwen Huang; Huaxing Qin; Qin Cen; Fei Meng; Liang Huang; Lifang Lin; Jian Pu; Di Yang
Journal:  Transl Cancer Res       Date:  2022-08       Impact factor: 0.496

5.  WT1 inhibits AML cell proliferation in a p53-dependent manner.

Authors:  Yiyun Yao; Xingxing Chai; Chen Gong; Lifang Zou
Journal:  Cell Cycle       Date:  2021-07-21       Impact factor: 5.173
  5 in total

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