Kemal Nas1, Erhan Capkin2, Abdullah Zübeyir Dagli3, Remzi Cevik3, Erkan Kilic4, Gamze Kilic4, Murat Karkucak2, Bekir Durmus5, Salih Ozgocmen4. 1. a Division of Rheumatology and Immunology, Department of Physical Medicine and Rehabilitation , Sakarya University, Faculty of Medicine , Sakarya , Turkey. 2. b Department of Physical Medicine and Rehabilitation , Karadeniz Technical University, Faculty of Medicine , Trabzon , Turkey. 3. c Division of Rheumatology, Department of Physical Medicine and Rehabilitation , Dicle University, Faculty of Medicine , Diyarbakir , Turkey. 4. d Division of Rheumatology, Department of Physical Medicine and Rehabilitation , Erciyes University, Faculty of Medicine , Kayseri , Turkey , and. 5. e Erenkoy Physical Medicine and Rehabilitation Hospital, Faculty of Health Sciences , Association of Public Hospitals Northern Anatolian Region of Istanbul , Istanbul , Turkey.
Abstract
OBJECTIVES: To assess gender related differences in a cohort of patients with psoriatic arthritis (PsA). METHODS: Consecutively recruited patients were included and underwent clinical, radiological and laboratory evaluation by using standardized protocol and case report forms. RESULTS: Women (n = 115) with PsA had higher symptom duration and body mass index (BMI), tender and swollen joint counts, disease activity score-28 joints (DAS28), Erythrocyte sedimentation rate (ESR) and poorer physical activity and fatigue than men (n = 72) with PsA. Psoriasis area and severity index (PASI) were higher in male patients. However quality of life (SF36 physical and mental component scores), articular pattern, extra-articular features (including uveitis, iritis) and family history for psoriasis, spondyloarthritis (SpA) (PsA and ankylosing spondylitis [AS]) were quite similar between men and women. CONCLUSIONS: Some of the clinical and laboratory variables tend to be different between men and women with PsA. The extent of quality of life and articular pattern seem to be similar in both genders. Men with PsA are more likely to have higher PASI scores and longer duration to develop arthritis after the onset of psoriasis, while women are more likely to have higher disease activity and report more fatigue and physical activity limitations.
OBJECTIVES: To assess gender related differences in a cohort of patients with psoriatic arthritis (PsA). METHODS: Consecutively recruited patients were included and underwent clinical, radiological and laboratory evaluation by using standardized protocol and case report forms. RESULTS:Women (n = 115) with PsA had higher symptom duration and body mass index (BMI), tender and swollen joint counts, disease activity score-28 joints (DAS28), Erythrocyte sedimentation rate (ESR) and poorer physical activity and fatigue than men (n = 72) with PsA. Psoriasis area and severity index (PASI) were higher in male patients. However quality of life (SF36 physical and mental component scores), articular pattern, extra-articular features (including uveitis, iritis) and family history for psoriasis, spondyloarthritis (SpA) (PsA and ankylosing spondylitis [AS]) were quite similar between men and women. CONCLUSIONS: Some of the clinical and laboratory variables tend to be different between men and women with PsA. The extent of quality of life and articular pattern seem to be similar in both genders. Men with PsA are more likely to have higher PASI scores and longer duration to develop arthritis after the onset of psoriasis, while women are more likely to have higher disease activity and report more fatigue and physical activity limitations.
Entities:
Keywords:
Gender; Psoriatic arthritis; Quality of life
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