Alexander K Schuster1, Norbert Pfeiffer1, Stefan Nickels1, Andreas Schulz2, René Höhn3, Philipp S Wild4, Harald Binder5, Thomas Münzel6, Manfred E Beutel7, Urs Vossmerbaeumer1. 1. Department of Ophthalmology University Medical Center Mainz, Mainz, Germany. 2. Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany. 3. Department of Ophthalmology University Medical Center Mainz, Mainz, Germany 3Department of Ophthalmology, University Hospital of Bern, Bern, Switzerland. 4. Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany 4Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-Universit. 5. Department of Biomedical Statistics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany. 6. DZHK (German Center for Cardiovascular Research), Partner Site Rhine-Main, Mainz, Germany 7Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany. 7. Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, Mainz, Germany.
Abstract
PURPOSE: Scheimpflug imaging allows quantitative analysis of the width of the anterior chamber angle. We report the population-based distribution of the anterior chamber angle width using this noncontact imaging technique and investigate associated factors. METHODS: A population-based cross-sectional study was carried out in Germany. A comprehensive ophthalmologic examination including refraction, biometry, and Scheimpflug imaging was performed. Automated measurement of the anterior chamber angle was performed in each anterior chamber quadrant. Exclusion criteria were previous ocular surgery or inadequate image quality. Association analyses were carried out to determine independently associated systemic and ocular factors for anterior chamber angle width using a generalized estimating equation model. RESULTS: A total of 3014 subjects (48% female) with a mean age of 58.6 ± 10.4 years were included in this study. The mean anterior chamber angle width was 32.6° ± 5.5°. Statistical analysis revealed an independent association between a smaller anterior chamber angle and female sex, higher age, and more hyperopic refraction. When including biometric parameters, shallow anterior chamber depth, shorter axial length, higher central corneal thickness, and lower corneal power were independently associated with a narrower mean anterior chamber angle width. CONCLUSIONS: These parameters are considered risk factors for angle-closure glaucoma.
PURPOSE: Scheimpflug imaging allows quantitative analysis of the width of the anterior chamber angle. We report the population-based distribution of the anterior chamber angle width using this noncontact imaging technique and investigate associated factors. METHODS: A population-based cross-sectional study was carried out in Germany. A comprehensive ophthalmologic examination including refraction, biometry, and Scheimpflug imaging was performed. Automated measurement of the anterior chamber angle was performed in each anterior chamber quadrant. Exclusion criteria were previous ocular surgery or inadequate image quality. Association analyses were carried out to determine independently associated systemic and ocular factors for anterior chamber angle width using a generalized estimating equation model. RESULTS: A total of 3014 subjects (48% female) with a mean age of 58.6 ± 10.4 years were included in this study. The mean anterior chamber angle width was 32.6° ± 5.5°. Statistical analysis revealed an independent association between a smaller anterior chamber angle and female sex, higher age, and more hyperopic refraction. When including biometric parameters, shallow anterior chamber depth, shorter axial length, higher central corneal thickness, and lower corneal power were independently associated with a narrower mean anterior chamber angle width. CONCLUSIONS: These parameters are considered risk factors for angle-closure glaucoma.
Authors: Alexander K Schuster; Norbert Pfeiffer; Stefan Nickels; Andreas Schulz; Philipp S Wild; Maria Blettner; Karl Lackner; Manfred E Beutel; Thomas Münzel; Urs Vossmerbaeumer Journal: J Ophthalmol Date: 2017-09-11 Impact factor: 1.909
Authors: Esther M Hoffmann; Fidan Aghayeva; Felix M Wagner; Achim Fiess; Markus Nagler; Thomas Münzel; Philipp S Wild; Manfred E Beutel; Irene Schmidtmann; Karl J Lackner; Norbert Pfeiffer; Alexander K Schuster Journal: Invest Ophthalmol Vis Sci Date: 2022-01-03 Impact factor: 4.799
Authors: Achim Fieß; Sandra Gißler; Eva Mildenberger; Michael S Urschitz; Agnes Fauer; Heike M Elflein; Fred Zepp; Bernhard Stoffelns; Norbert Pfeiffer; Alexander K Schuster Journal: Children (Basel) Date: 2022-02-18