Literature DB >> 27413717

Recurrent "pneumonia" in left lower lobe lasting for 8 years: a case report.

Dong-Mei Yuan1, Yan-Wen Yao1, Qian Li1, Chen-Yang Liu1, Pei Li1, E-Hong Cao1, Xin-Wu Xiao1, Xin Su1, Yong Song1.   

Abstract

Bronchioloalveolar carcinoma (BAC) is a unique lung neoplasm with variable forms, such as single nodular, multifocal and lobar pneumonic types. The pneumonic type BAC is often difficult to differentiate from pneumonia. Here we present a case of 63-year-old Chinese male, who had recurrent cough, white sputum with pneumonic lesions in left lower lobe. He suffered from lung biopsies for three times, and finally diagnosed as high differentiated adenocarcinoma 8 years later. He was treated with four cycles of pemetrexed and cisplatin, and four cycles of docetaxel and nedaplatin. However, he did not achieve disease stabilization and is still under follow up. This case suggests that, pneumonic type adenocarcinoma may radiographically and clinically resemble infectious pneumonia. Lack of fever and leukocytosis, no response to antibiotics, air bronchogram, and accompanied nodules or patches in computed tomography (CT) scans should raise suspicion about the diagnosis of pneumonia. Lung biopsy might be the only means of ruling in a diagnosis of BAC.

Entities:  

Keywords:  Pneumonic-type adenocarcinoma (P-ADCs); bronchioloalveolar carcinoma (BAC); lung biopsy

Year:  2016        PMID: 27413717      PMCID: PMC4931138          DOI: 10.21037/tlcr.2016.05.04

Source DB:  PubMed          Journal:  Transl Lung Cancer Res        ISSN: 2218-6751


  20 in total

1.  Images in clinical medicine. Bronchoalveolar-cell carcinoma.

Authors:  Richard Booton; B K Jacob
Journal:  N Engl J Med       Date:  2002-01-10       Impact factor: 91.245

2.  Clinical features of patients with stage IIIB and IV bronchioloalveolar carcinoma of the lung.

Authors:  O S Breathnach; N Ishibe; J Williams; R I Linnoila; N Caporaso; B E Johnson
Journal:  Cancer       Date:  1999-10-01       Impact factor: 6.860

3.  Bronchiolar carcinoma (alveolar cell), another great imitator; a review of 41 cases.

Authors:  L G Ludington; J J Verska; T Howard; G Kypridakis; L A Brewer
Journal:  Chest       Date:  1972-06       Impact factor: 9.410

4.  Southwestern oncology group phase II trial (S0526) of pemetrexed in bronchioloalveolar carcinoma subtypes of advanced adenocarcinoma.

Authors:  Derick H M Lau; James Moon; Angela M Davies; Rachel E Sanborn; Fred R Hirsch; Wilbur A Franklin; Janet C Ruzich; Mary W Redman; David R Gandara
Journal:  Clin Lung Cancer       Date:  2013-02-14       Impact factor: 4.785

5.  Expression of thyroid transcription factor-1, cytokeratin 7, and cytokeratin 20 in bronchioloalveolar carcinomas: an immunohistochemical evaluation of 67 cases.

Authors:  Sean K Lau; Matthew J Desrochers; Daniel J Luthringer
Journal:  Mod Pathol       Date:  2002-05       Impact factor: 7.842

6.  Bronchioloalveolar carcinoma masquerading as pneumonia.

Authors:  William H Thompson
Journal:  Respir Care       Date:  2004-11       Impact factor: 2.258

7.  Prognosis and recurrent patterns in bronchioloalveolar carcinoma.

Authors:  Y Y Liu; Y M Chen; M H Huang; R P Perng
Journal:  Chest       Date:  2000-10       Impact factor: 9.410

8.  Staging of non-small-cell lung cancer with integrated positron-emission tomography and computed tomography.

Authors:  Didier Lardinois; Walter Weder; Thomas F Hany; Ehab M Kamel; Stephan Korom; Burkhardt Seifert; Gustav K von Schulthess; Hans C Steinert
Journal:  N Engl J Med       Date:  2003-06-19       Impact factor: 91.245

9.  Diagnostic value of bronchoalveolar lavage in peripheral lung cancer.

Authors:  J de Gracia; C Bravo; M Miravitlles; N Tallada; R Orriols; J Bellmunt; M Vendrell; F Morell
Journal:  Am Rev Respir Dis       Date:  1993-03

10.  EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia.

Authors:  Alvaro Taus; Flavio Zuccarino; Carlos Trampal; Edurne Arriola
Journal:  Case Rep Pulmonol       Date:  2012-08-23
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  2 in total

1.  Unusual presentation of lepidic adenocarcinoma in a healthy female.

Authors:  Zaheer Akhtar; Leah Laageide; Julian Robles; Christopher Winters; Geoffrey C Wall; James Mallen; Zeeshan Jawa
Journal:  BMC Pulm Med       Date:  2022-05-16       Impact factor: 3.320

2.  Unusual presentation of primary lung adenocarcinoma mimicking pneumonia: Case report and literature review.

Authors:  Asil Daoud; Amir Laktineh; Said El Zein; Ayman O Soubani
Journal:  Respir Med Case Rep       Date:  2019-06-14
  2 in total

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