Literature DB >> 27411820

Semax prevents learning and memory inhibition by heavy metals.

A N Inozemtsev1, S B Bokieva2, O V Karpukhina3,2, K Z Gumargalieva4, A A Kamensky3, N F Myasoedov5.   

Abstract

Separate and joint effect of Semax, ascorbic acid, lead diacetate, and ammonium molybdate on avoidance conditioning in rats was studied. It was established that the heavy metal salts inhibited the avoidance response, and the peptide counteracted this inhibition as strongly as ascorbic acid or to a comparable degree. These findings confirm the antioxidant properties of Semax.

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Year:  2016        PMID: 27411820     DOI: 10.1134/S0012496616030066

Source DB:  PubMed          Journal:  Dokl Biol Sci        ISSN: 0012-4966


  6 in total

Review 1.  Metals, oxidative stress and neurodegenerative disorders.

Authors:  Klaudia Jomova; Dagmar Vondrakova; Michael Lawson; Marian Valko
Journal:  Mol Cell Biochem       Date:  2010-08-22       Impact factor: 3.396

2.  Effects of combined treatment with heavy metals and piracetam on learning and memory in rats.

Authors:  A N Inozemtsev; S B Bokieva; O V Karpukhina; K Z Gumargalieva
Journal:  Dokl Biol Sci       Date:  2008 Sep-Oct

3.  Semax prevents functional impairments of avoidance response in rats.

Authors:  A N Inozemtsev; A E Agapitova; S B Bokieva; N G Levitskaya; A A Kamenskii; N F Myasoedov
Journal:  Dokl Biol Sci       Date:  2013-03-12

4.  Effect of Ginkgo biloba Extract on Lead-Induced Oxidative Stress in Different Regions of Rat Brain.

Authors:  Prabhakara Rao Yallapragada; Manoj Kumar Velaga
Journal:  J Environ Pathol Toxicol Oncol       Date:  2015       Impact factor: 3.567

5.  Ameliorative effects of Bacopa monniera on lead-induced oxidative stress in different regions of rat brain.

Authors:  Manoj Kumar Velaga; Charan Kumar Basuri; Kendra S Robinson Taylor; Prabhakara Rao Yallapragada; Sharada Rajanna; Bettaiya Rajanna
Journal:  Drug Chem Toxicol       Date:  2013-12-12       Impact factor: 3.356

Review 6.  Free radicals: properties, sources, targets, and their implication in various diseases.

Authors:  Alugoju Phaniendra; Dinesh Babu Jestadi; Latha Periyasamy
Journal:  Indian J Clin Biochem       Date:  2014-07-15
  6 in total
  1 in total

1.  Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia-Reperfusion in Rats.

Authors:  Ivan B Filippenkov; Vasily V Stavchansky; Alina E Denisova; Vadim V Yuzhakov; Larisa E Sevan'kaeva; Olga Y Sudarkina; Veronika G Dmitrieva; Leonid V Gubsky; Nikolai F Myasoedov; Svetlana A Limborska; Lyudmila V Dergunova
Journal:  Genes (Basel)       Date:  2020-06-22       Impact factor: 4.096

  1 in total

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