Literature DB >> 27411696

[Necrotizing funisitis : Histopathological indicator of occult congenital syphilis].

K Hussein1, C Peter2, L Sedlacek3, C von Kaisenberg4, H H Kreipe5.   

Abstract

Congenital syphilis is a rare disease in central Europe. Placental changes may be non-specific but a typical finding is necrotizing funisitis of the umbilical cord. In a case report we describe how the histopathological incidental finding of B lymphocyte-rich, necrotizing funisitis led to the diagnosis of a previously unknown Treponema pallidum infection in parents and their newborn child. The pathological suspicion of congenital syphilis, although rare, has implications for the clinical management (serological evaluation of parents and child as well as the social environment, evaluation of viral coinfection and treatment decision) and is a notifiable disease.

Entities:  

Keywords:  Serological testing; Social environment; Therapy decision; Treponema pallidum; Viral coinfection

Mesh:

Year:  2017        PMID: 27411696     DOI: 10.1007/s00292-016-0177-5

Source DB:  PubMed          Journal:  Pathologe        ISSN: 0172-8113            Impact factor:   1.011


  12 in total

1.  Characterization of inflammation in syphilitic villitis and in villitis of unknown etiology.

Authors:  Payal Kapur; Dinesh Rakheja; Ana M Gomez; Jeanne Sheffield; Pablo Sanchez; Beverly Barton Rogers
Journal:  Pediatr Dev Pathol       Date:  2004-07-30

2.  Syphilis of the Placenta.

Authors:  P J Kearns
Journal:  Can Med Assoc J       Date:  1936-06       Impact factor: 8.262

3.  Syphilis is back: presentation of three cases at the ENT department.

Authors:  M Gugatschka; G P Hammer; W Koele; H Reiter; G Friedrich; D Lang-Loidolt
Journal:  B-ENT       Date:  2012       Impact factor: 0.082

Review 4.  Curse on two generations: a history of congenital syphilis.

Authors:  Michael Obladen
Journal:  Neonatology       Date:  2013-03-13       Impact factor: 4.035

5.  Nonsyphilitic spirochetosis in second-trimester fetuses.

Authors:  C Abramowsky; P Beyer-Patterson; E Cortinas
Journal:  Pediatr Pathol       Date:  1991 Nov-Dec

6.  Hemophagocytosis: the cause of anemia and thrombocytopenia in congenital syphilis.

Authors:  Nese Yarali; Ismail Balaban; Nesibe Akyurek; Sit Ucar; Pelin Zorlu
Journal:  Pediatr Hematol Oncol       Date:  2009-09       Impact factor: 1.969

Review 7.  The role of co-infections in mother-to-child transmission of HIV.

Authors:  Caroline C King; Sascha R Ellington; Athena P Kourtis
Journal:  Curr HIV Res       Date:  2013-01       Impact factor: 1.581

8.  Pathology of the umbilical cord in congenital syphilis: analysis of 25 specimens using histochemistry and immunofluorescent antibody to Treponema pallidum.

Authors:  D A Schwartz; S A Larsen; C Beck-Sague; M Fears; R J Rice
Journal:  Hum Pathol       Date:  1995-07       Impact factor: 3.466

9.  Estimating disease burden of maternal syphilis and associated adverse pregnancy outcomes in India, Nigeria, and Zambia in 2012.

Authors:  Xiang-Sheng Chen; Sunil Khaparde; Turlapati L N Prasad; Vani Srinivas; Chukwuma Anyaike; Gbenga Ijaodola; Evelyn Ngige; Grace Tembo Mumba; Carolline Phiri; Bushimbwa Tambatamba; Laxmikant Chavan; Nicole Seguy; Taiwo A Oyelade; Malumo Sarai Bvulani; Lori M Newman
Journal:  Int J Gynaecol Obstet       Date:  2015-04-24       Impact factor: 3.561

10.  Antenatal screening for HIV, hepatitis B and syphilis in the Netherlands is effective.

Authors:  Eline L M Op de Coul; Susan Hahné; Yolanda W M van Weert; Petra Oomen; Colette Smit; Kitty P B van der Ploeg; Daan W Notermans; Kees Boer; Marianne A B van der Sande
Journal:  BMC Infect Dis       Date:  2011-06-30       Impact factor: 3.090

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.