| Literature DB >> 27411580 |
Gauri Deb1, Tim C P Somervaille2.
Abstract
E proteins and their functional antagonists, the ID proteins, have significant roles in normal hematopoiesis. In this issue of Cancer Cell, Ghisi et al. show that high ID2 levels antagonize self-renewal and promote differentiation of leukemic stem cells in the MLL-translocated molecular subtype of acute myeloid leukemia.Entities:
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Year: 2016 PMID： 27411580 DOI： 10.1016/j.ccell.2016.06.006
Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743