| Literature DB >> 27411579 |
Tatsuro Watanabe1, Patricia Ernst2.
Abstract
In this issue of Cancer Cell, Stavropoulou et al. report that expression of the MLL-AF9 fusion results in acute myelogenous leukemia (AML) with different behaviors depending on cell context, which leads them to identify a transcriptional signature surprisingly resembling that of the epithelial-to-mesenchymal (EMT) transition, correlating with aggressiveness of disease.Entities:
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Year: 2016 PMID： 27411579 DOI： 10.1016/j.ccell.2016.06.011
Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743