| Literature DB >> 27411006 |
Adriana R Mantegazza1, Michael S Marks2.
Abstract
Mitochondrial dysfunction and T cell autoimmunity have been independently implicated in Parkinson disease pathogenesis. In a recent publication in Cell, Matheoud et al. (2016) link them by describing a new mechanism, activated in familial forms of Parkinson disease, in which mitochondrial proteins are processed for recognition by CD8+ T cells.Entities:
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Year: 2016 PMID: 27411006 PMCID: PMC4993039 DOI: 10.1016/j.cmet.2016.06.022
Source DB: PubMed Journal: Cell Metab ISSN: 1550-4131 Impact factor: 27.287