Literature DB >> 27411004

Elevated GDF11 Is a Risk Factor for Age-Related Frailty and Disease in Humans.

David J Glass1.   

Abstract

GDF11 was reported to decline with age and to have muscle and heart rejuvenating effects. These reports were disputed. A Cell Metabolism paper now shows that in human beings, GDF11 does not decline with age and is actually a risk factor for frailty and other morbidities (Schafer et al., 2016).
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 27411004     DOI: 10.1016/j.cmet.2016.06.017

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  8 in total

1.  The clinical impact and biological mechanisms of skeletal muscle aging.

Authors:  Zaira Aversa; Xu Zhang; Roger A Fielding; Ian Lanza; Nathan K LeBrasseur
Journal:  Bone       Date:  2019-05-22       Impact factor: 4.398

2.  Growth differentiation factor 11 (GDF11) has pronounced effects on skin biology.

Authors:  Jolanta Idkowiak-Baldys; Uma Santhanam; Sean M Buchanan; Kathleen Lindahl Pfaff; Lee L Rubin; John Lyga
Journal:  PLoS One       Date:  2019-06-10       Impact factor: 3.240

Review 3.  GDF11 Implications in Cancer Biology and Metabolism. Facts and Controversies.

Authors:  Arturo Simoni-Nieves; Monserrat Gerardo-Ramírez; Gibrán Pedraza-Vázquez; Lisette Chávez-Rodríguez; Leticia Bucio; Verónica Souza; Roxana U Miranda-Labra; Luis E Gomez-Quiroz; María Concepción Gutiérrez-Ruiz
Journal:  Front Oncol       Date:  2019-10-15       Impact factor: 6.244

Review 4.  Myostatin/Activin Receptor Ligands in Muscle and the Development Status of Attenuating Drugs.

Authors:  Buel D Rodgers; Christopher W Ward
Journal:  Endocr Rev       Date:  2022-03-09       Impact factor: 25.261

5.  Growth differentiation factor 11 attenuates cardiac ischemia reperfusion injury via enhancing mitochondrial biogenesis and telomerase activity.

Authors:  Lin Chen; Guangjin Luo; Yameng Liu; Hairuo Lin; Cankun Zheng; Dongxiao Xie; Yingqi Zhu; Lu Chen; Xiaoxia Huang; Donghong Hu; Jiahe Xie; Zhenhuan Chen; Wangjun Liao; Jianping Bin; Qiancheng Wang; Yulin Liao
Journal:  Cell Death Dis       Date:  2021-07-02       Impact factor: 8.469

6.  GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation.

Authors:  Weiqing Liu; Liyan Zhou; Chenchen Zhou; Shiwen Zhang; Junjun Jing; Liang Xie; Ningyuan Sun; Xiaobo Duan; Wei Jing; Xing Liang; Hu Zhao; Ling Ye; Qianming Chen; Quan Yuan
Journal:  Nat Commun       Date:  2016-09-22       Impact factor: 14.919

Review 7.  Role of growth differentiation factor 11 in development, physiology and disease.

Authors:  Yonghui Zhang; Yong Wei; Dan Liu; Feng Liu; Xiaoshan Li; Lianhong Pan; Yi Pang; Dilong Chen
Journal:  Oncotarget       Date:  2017-08-14

8.  Relationship of muscle function to circulating myostatin, follistatin and GDF11 in older women and men.

Authors:  Elizaveta Fife; Joanna Kostka; Łukasz Kroc; Agnieszka Guligowska; Małgorzata Pigłowska; Bartłomiej Sołtysik; Agnieszka Kaufman-Szymczyk; Krystyna Fabianowska-Majewska; Tomasz Kostka
Journal:  BMC Geriatr       Date:  2018-08-30       Impact factor: 3.921

  8 in total

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