OBJECTIVE: To identify the main bacterial species associated with community-acquired urinary tract infection (UTI) and to assess the pattern of ciprofloxacin susceptibility among bacteria isolated from urine cultures. METHODS: We conducted a retrospective study in all the patients with community-acquired UTI seen in Santa Helena Laboratory, Camaçari, Bahia, Brazil during five years (2010-2014). All individuals who had a positive urine culture result were included in this study. RESULTS: A total of 1,641 individuals met the inclusion criteria. Despite the fact that participants were female, we observed a higher rate of resistance to ciprofloxacin in males. The most frequent pathogens identified in urine samples were Escherichia coli, Klebsiella pneumoniae and Staphylococcus saprophyticus. Antimicrobial resistance has been observed mainly for ampicillin, sulfamethoxazole + trimethoprim and ciprofloxacin. Moreover, E. coli has shown the highest rate of ciprofloxacin resistance, reaching 36% of ciprofloxacin resistant strains in 2014. CONCLUSION: The rate of bacterial resistance to ciprofloxacin observed in the studied population is much higher than expected, prompting the need for rational use of this antibiotic, especially in infections caused by E. coli. Prevention of bacterial resistance can be performed through control measures to limit the spread of resistant microorganisms and a rational use of antimicrobial policy.
OBJECTIVE: To identify the main bacterial species associated with community-acquired urinary tract infection (UTI) and to assess the pattern of ciprofloxacin susceptibility among bacteria isolated from urine cultures. METHODS: We conducted a retrospective study in all the patients with community-acquired UTI seen in Santa Helena Laboratory, Camaçari, Bahia, Brazil during five years (2010-2014). All individuals who had a positive urine culture result were included in this study. RESULTS: A total of 1,641 individuals met the inclusion criteria. Despite the fact that participants were female, we observed a higher rate of resistance to ciprofloxacin in males. The most frequent pathogens identified in urine samples were Escherichia coli, Klebsiella pneumoniae and Staphylococcus saprophyticus. Antimicrobial resistance has been observed mainly for ampicillin, sulfamethoxazole + trimethoprim and ciprofloxacin. Moreover, E. coli has shown the highest rate of ciprofloxacin resistance, reaching 36% of ciprofloxacin resistant strains in 2014. CONCLUSION: The rate of bacterial resistance to ciprofloxacin observed in the studied population is much higher than expected, prompting the need for rational use of this antibiotic, especially in infections caused by E. coli. Prevention of bacterial resistance can be performed through control measures to limit the spread of resistant microorganisms and a rational use of antimicrobial policy.
Authors: A Bartoloni; L Pallecchi; E Riccobono; A Mantella; D Magnelli; T Di Maggio; A L Villagran; Y Lara; C Saavedra; M Strohmeyer; F Bartalesi; C Trigoso; G M Rossolini Journal: Clin Microbiol Infect Date: 2012-03-13 Impact factor: 8.067
Authors: James R Johnson; Brian Johnston; Michael A Kuskowski; Evgeni V Sokurenko; Veronika Tchesnokova Journal: Antimicrob Agents Chemother Date: 2015-05-18 Impact factor: 5.191
Authors: Marcelle Cristina da Silva Pires; Karla de Sousa Frota; Paulo de Oliveira Martins Junior; Amabel Fernandes Correia; Juan José Cortez-Escalante; Celeste Aída Silveira Journal: Rev Soc Bras Med Trop Date: 2007 Nov-Dec Impact factor: 1.581
Authors: Majed M Masadeh; Karem H Alzoubi; Bashar M Al-Taani; Majd M Masadeh; Zainah O Aburashed; Nasr Alrabadi Journal: Clin Pharmacol Date: 2020-10-12
Authors: Deepali Sharma; Rahul P Patel; Syed Tabish R Zaidi; Md Moklesur Rahman Sarker; Qi Ying Lean; Long C Ming Journal: Front Pharmacol Date: 2017-08-21 Impact factor: 5.810