Literature DB >> 27410464

IL-1 family cytokines in cancer immunity - a matter of life and death.

Javier Mora, Andreas Weigert.   

Abstract

IL-1 cytokines constitute a family of biologically active proteins with pleiotropic function especially in immunity. Both protective as well as deleterious properties of individual IL-1 family cytokines in tumor biology have been described. The function of IL-1-family cytokines depends on the producing source, the present (inflammatory) microenvironment and N-terminal proteolytical processing. Each of these determinants is shaped by different modes of cell death. Here we summarize the properties of IL-1 family cytokines in tumor biology, and how they are modulated by cell death.

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Year:  2016        PMID： 27410464     DOI： 10.1515/hsz-2016-0215

Source DB:  PubMed          Journal:  Biol Chem        ISSN： 1431-6730            Impact factor:   3.915


  7 in total

1.  Kompetitive Allele Specific PCR (KASP™) genotyping of 48 polymorphisms at different caprine loci in French Alpine and Saanen goat breeds and their association with milk composition.

Authors:  Szilvia Kusza; Ludovic Toma Cziszter; Daniela Elena Ilie; Maria Sauer; Ioan Padeanu; Dinu Gavojdian
Journal:  PeerJ       Date:  2018-02-21       Impact factor: 2.984

Review 2.  Inflammasomes and Cancer: The Dynamic Role of the Inflammasome in Tumor Development.

Authors:  Melvin Kantono; Beichu Guo
Journal:  Front Immunol       Date:  2017-09-12       Impact factor: 7.561

Review 3.  Immunobiological Properties and Clinical Applications of Interleukin-38 for Immune-Mediated Disorders: A Systematic Review Study.

Authors:  Abdolreza Esmaeilzadeh; Nazila Bahmaie; Elham Nouri; Mohammad Javad Hajkazemi; Maryam Zareh Rafie
Journal:  Int J Mol Sci       Date:  2021-11-21       Impact factor: 5.923

Review 4.  IL-1 Family Cytokines in Inflammatory Dermatoses: Pathogenetic Role and Potential Therapeutic Implications.

Authors:  Helena Iznardo; Luís Puig
Journal:  Int J Mol Sci       Date:  2022-08-22       Impact factor: 6.208

5.  Difference in mortality rates in hospitalized COVID-19 patients identified by cytokine profile clustering using a machine learning approach: An outcome prediction alternative.

Authors:  Ana Cristina Castro-Castro; Lucia Figueroa-Protti; Jose Arturo Molina-Mora; María Paula Rojas-Salas; Danae Villafuerte-Mena; María José Suarez-Sánchez; Alfredo Sanabría-Castro; Carolina Boza-Calvo; Leonardo Calvo-Flores; Mariela Solano-Vargas; Juan José Madrigal-Sánchez; Mario Sibaja-Campos; Juan Ignacio Silesky-Jiménez; José Miguel Chaverri-Fernández; Andrés Soto-Rodríguez; Ann Echeverri-McCandless; Sebastián Rojas-Chaves; Denis Landaverde-Recinos; Andreas Weigert; Javier Mora
Journal:  Front Med (Lausanne)       Date:  2022-09-20

Review 6.  Iron Handling in Tumor-Associated Macrophages-Is There a New Role for Lipocalin-2?

Authors:  Michaela Jung; Andreas Weigert; Christina Mertens; Claudia Rehwald; Bernhard Brüne
Journal:  Front Immunol       Date:  2017-09-20       Impact factor: 7.561

Review 7.  Key Factor Regulating Inflammatory Microenvironment, Metastasis, and Resistance in Breast Cancer: Interleukin-1 Signaling.

Authors:  Fengjie Liu; Lihong Li; Meng Lan; Tengteng Zou; Zhaodi Kong; Tiange Cai; Xiao Yu Wu; Yu Cai
Journal:  Mediators Inflamm       Date:  2021-09-23       Impact factor: 4.711
  7 in total

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