Literature DB >> 27410046

Clues to NPC1-mediated cholesterol export from lysosomes.

Suzanne R Pfeffer1.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 27410046      PMCID： PMC4961152          DOI： 10.1073/pnas.1608530113

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


× No keyword cloud information.
  20 in total

1.  Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding.

Authors:  Maika S Deffieu; Suzanne R Pfeffer
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-07       Impact factor: 11.205

2.  Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein.

Authors:  Rodney E Infante; Lina Abi-Mosleh; Arun Radhakrishnan; Jarrod D Dale; Michael S Brown; Joseph L Goldstein
Journal:  J Biol Chem       Date:  2007-11-06       Impact factor: 5.157

3.  Topological analysis of Niemann-Pick C1 protein reveals that the membrane orientation of the putative sterol-sensing domain is identical to those of 3-hydroxy-3-methylglutaryl-CoA reductase and sterol regulatory element binding protein cleavage-activating protein.

Authors:  J P Davies; Y A Ioannou
Journal:  J Biol Chem       Date:  2000-08-11       Impact factor: 5.157

Review 4.  A receptor-mediated pathway for cholesterol homeostasis.

Authors:  M S Brown; J L Goldstein
Journal:  Science       Date:  1986-04-04       Impact factor: 47.728

5.  Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis.

Authors:  E D Carstea; J A Morris; K G Coleman; S K Loftus; D Zhang; C Cummings; J Gu; M A Rosenfeld; W J Pavan; D B Krizman; J Nagle; M H Polymeropoulos; S L Sturley; Y A Ioannou; M E Higgins; M Comly; A Cooney; A Brown; C R Kaneski; E J Blanchette-Mackie; N K Dwyer; E B Neufeld; T Y Chang; L Liscum; J F Strauss; K Ohno; M Zeigler; R Carmi; J Sokol; D Markie; R R O'Neill; O P van Diggelen; M Elleder; M C Patterson; R O Brady; M T Vanier; P G Pentchev; D A Tagle
Journal:  Science       Date:  1997-07-11       Impact factor: 47.728

6.  Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop.

Authors:  Rodney E Infante; Arun Radhakrishnan; Lina Abi-Mosleh; Lisa N Kinch; Michael L Wang; Nick V Grishin; Joseph L Goldstein; Michael S Brown
Journal:  J Biol Chem       Date:  2007-11-06       Impact factor: 5.157

7.  Discovery of oxysterol-derived pharmacological chaperones for NPC1: implication for the existence of second sterol-binding site.

Authors:  Kenji Ohgane; Fumika Karaki; Kosuke Dodo; Yuichi Hashimoto
Journal:  Chem Biol       Date:  2013-03-21

8.  Structural basis of sterol binding by NPC2, a lysosomal protein deficient in Niemann-Pick type C2 disease.

Authors:  Sujuan Xu; Brian Benoff; Heng-Ling Liou; Peter Lobel; Ann M Stock
Journal:  J Biol Chem       Date:  2007-06-14       Impact factor: 5.157

9.  Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain.

Authors:  Nobutaka Ohgami; Dennis C Ko; Matthew Thomas; Matthew P Scott; Catherine C Y Chang; Ta-Yuan Chang
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-16       Impact factor: 11.205

10.  Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions.

Authors:  Yuguang Zhao; Jingshan Ren; Karl Harlos; David I Stuart
Journal:  FEBS Lett       Date:  2016-02-23       Impact factor: 4.124
View more
  10 in total

1.  Dietary plant stanol ester supplementation reduces peripheral symptoms in a mouse model of Niemann-Pick type C1 disease.

Authors:  Inês Magro Dos Reis; Tom Houben; Yvonne Oligschläger; Leoni Bücken; Hellen Steinbusch; David Cassiman; Dieter Lütjohann; Marit Westerterp; Jos Prickaerts; Jogchum Plat; Ronit Shiri-Sverdlov
Journal:  J Lipid Res       Date:  2020-04-14       Impact factor: 5.922

Review 2.  Exacerbating and reversing lysosomal storage diseases: from yeast to humans.

Authors:  Tamayanthi Rajakumar; Andrew B Munkacsi; Stephen L Sturley
Journal:  Microb Cell       Date:  2017-08-25

Review 3.  Recent neuroimaging, neurophysiological, and neuropathological advances for the understanding of NPC.

Authors:  Alberto Benussi; Maria Sofia Cotelli; Alessandro Padovani; Barbara Borroni
Journal:  F1000Res       Date:  2018-02-15

4.  Identifying the structure-activity relationship of leelamine necessary for inhibiting intracellular cholesterol transport.

Authors:  Raghavendra Gowda; Gajanan S Inamdar; Omer Kuzu; Saketh S Dinavahi; Jacek Krzeminski; Madhu Babu Battu; Sreedhara R Voleti; Shantu Amin; Gavin P Robertson
Journal:  Oncotarget       Date:  2017-04-25

5.  Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.

Authors:  Zhiyuan Lu; Lixia Huang; Yanxia Li; Yan Xu; Ruihao Zhang; Qian Zhou; Qi Sun; Yi Lu; Junjie Chen; Yuemao Shen; Jian Li; Baobing Zhao
Journal:  Adv Sci (Weinh)       Date:  2021-11-05       Impact factor: 16.806

6.  Proteomic analysis of s-acylated proteins in human retinal pigment epithelial cells and the role of palmitoylation of Niemann-Pick type C1 protein in cholesterol transport.

Authors:  Jia Kai Li; Yu Qing Rao; Siew Kwan Koh; Peiquan Zhao; Lei Zhou; Jing Li
Journal:  Front Aging Neurosci       Date:  2022-10-03       Impact factor: 5.702

7.  Molecular dynamics study with mutation shows that N-terminal domain structural re-orientation in Niemann-Pick type C1 is required for proper alignment of cholesterol transport.

Authors:  Hye-Jin Yoon; Hyunah Jeong; Hyung Ho Lee; Soonmin Jang
Journal:  J Neurochem       Date:  2020-09-16       Impact factor: 5.546

8.  Pneumococcal Immunization Reduces Neurological and Hepatic Symptoms in a Mouse Model for Niemann-Pick Type C1 Disease.

Authors:  Tom Houben; Inês Magro Dos Reis; Yvonne Oligschlaeger; Hellen Steinbusch; Marion J J Gijbels; Tim Hendrikx; Christoph J Binder; David Cassiman; Marit Westerterp; Jos Prickaerts; Ronit Shiri-Sverdlov
Journal:  Front Immunol       Date:  2019-01-07       Impact factor: 7.561

9.  A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.

Authors:  Dick J H van den Boomen; Agata Sienkiewicz; Ilana Berlin; Marlieke L M Jongsma; Daphne M van Elsland; J Paul Luzio; Jacques J C Neefjes; Paul J Lehner
Journal:  Nat Commun       Date:  2020-11-03       Impact factor: 14.919

10.  Cholesterol binding to the sterol-sensing region of Niemann Pick C1 protein confines dynamics of its N-terminal domain.

Authors:  Vikas Dubey; Behruz Bozorg; Daniel Wüstner; Himanshu Khandelia
Journal:  PLoS Comput Biol       Date:  2020-10-06       Impact factor: 4.475
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.