Jelena Lecic1, Sasa Cakic2, Ognjenka Janjic Pavlovic3, Ana Cicmil1, Olivera Vukotic1, Vanja Petrovic4, Smiljka Cicmil1. 1. a Department of Periodontology and Oral Medicine , University of East Sarajevo, Faculty of Medicine, Dentistry Program , Foca , Bosnia and Herzegovina ; 2. b Department of Periodontology and Oral Medicine , University of Belgrade, Faculty of Dental Medicine , Belgrade , Serbia ; 3. c Department of Prosthodontics , University of East Sarajevo, Faculty of Medicine, Dentistry Program , Foca , Bosnia and Herzegovina ; 4. d Department of Pediatric and Preventive Dentistry , University of Belgrade, Faculty of Dental Medicine , Belgrade , Serbia.
Abstract
OBJECTIVE: The aim of this study was to evaluate clinical efficacy of different chlorhexidine gluconate (CHX) preparations applied subgingivally as an adjunct to scaling and root planing (SRP). MATERIAL AND METHODS: A total of 120 periodontal pockets was included in this randomized, controlled, split mouth designed study. According to protocols used in treatment, periodontal pockets were assigned to experimental and control groups as follows: CHX solution as an addition to SRP versus control SRP group; CHX gel as an addition to SRP versus control SRP; CHX chip as an addition to SRP versus control SRP group. Following clinical parameters were recorded at baseline, one and three months after the baseline: plaque index (PI), probing pocket depth (PPD), bleeding index (BI) and clinical attachment level (CAL). RESULTS: The most significant improvements were found concerning PI in CHX solution with SRP and CHX gel with SRP groups over controls at one month recall, as well as concerning BI and PPD in CHX chip with SRP group over SRP alone at three-month recall. CONCLUSION: Results of this study favour combination therapy using CHX chip as an adjunct to SRP due to greater improvements in BI and PPD compared to those obtained by SRP alone in the treatment of chronic periodontitis.
RCT Entities:
OBJECTIVE: The aim of this study was to evaluate clinical efficacy of different chlorhexidine gluconate (CHX) preparations applied subgingivally as an adjunct to scaling and root planing (SRP). MATERIAL AND METHODS: A total of 120 periodontal pockets was included in this randomized, controlled, split mouth designed study. According to protocols used in treatment, periodontal pockets were assigned to experimental and control groups as follows: CHX solution as an addition to SRP versus control SRP group; CHX gel as an addition to SRP versus control SRP; CHX chip as an addition to SRP versus control SRP group. Following clinical parameters were recorded at baseline, one and three months after the baseline: plaque index (PI), probing pocket depth (PPD), bleeding index (BI) and clinical attachment level (CAL). RESULTS: The most significant improvements were found concerning PI in CHX solution with SRP and CHX gel with SRP groups over controls at one month recall, as well as concerning BI and PPD in CHX chip with SRP group over SRP alone at three-month recall. CONCLUSION: Results of this study favour combination therapy using CHX chip as an adjunct to SRP due to greater improvements in BI and PPD compared to those obtained by SRP alone in the treatment of chronic periodontitis.
Entities:
Keywords:
Periodontitis; antimicrobials; chlorhexidine gluconate; local drug delivery; scaling and root planing
Authors: Sopita Ruangcharoen; Waraporn Suwannarong; Marie Rossini Carmela T Lachica; Jan G M Bolscher; Kamran Nazmi; Watcharee Khunkitti; Suwimol Taweechaisupapong Journal: World J Microbiol Biotechnol Date: 2017-08-19 Impact factor: 3.312
Authors: Cleber Davi Del Rei Daltro Rosa; Jéssica Marcela de Luna Gomes; Sandra Lúcia Dantas de Moraes; Cleidiel Aparecido Araujo Lemos; Tatiana Prosini da Fonte; João Pedro Justino de Oliveira Limirio; Eduardo Piza Pellizzer Journal: Saudi Dent J Date: 2020-11-11