Ibrahim Yilmaz1, Semih Akkaya2, Mehmet Isyar3, Ahmet Güray Batmaz4, Olcay Guler4, Kadir Oznam4, Akin Ugras4, Mahir Mahiroğullari5. 1. Republic of Turkey Ministry of Health, State Hospital, Department of Pharmacovigilance, Materiovigilance and Rational Use of Drugs, 59100 Tekirdag, Turkey. 2. Pamukkale University School of Medicine, Department of Orthopaedic and Traumatology, 20070 Denizli, Turkey. 3. Central Hospital Health Group, Department of Orthopaedic and Traumatology, 34742 Istanbul, Turkey. 4. Istanbul Medipol University School of Medicine, Department of Orthopaedic and Traumatology, 34214 Istanbul, Turkey. 5. Memorial Health Group, Department of Orthopaedic and Traumatology, 34384 Istanbul, Turkey.
Abstract
AIM: We aimed to reveal whether there are prospective suggestions for effective and standard platelet-rich plasma applications. METHODS: We searched for clinical trials and traced all the references of incorporated documents. RESULTS: In literature, there was no study indicating which disease is treated by which mechanism of action, how much dose and content are prepared and applied, when the treatment is applied and how many cures are applied. CONCLUSION: Guides introducing which concentrations of PRP are used for which diseases are to be prepared immediately by a committee which is comprised of primarily orthopedists, clinical pharmacologists and toxicologists.
AIM: We aimed to reveal whether there are prospective suggestions for effective and standard platelet-rich plasma applications. METHODS: We searched for clinical trials and traced all the references of incorporated documents. RESULTS: In literature, there was no study indicating which disease is treated by which mechanism of action, how much dose and content are prepared and applied, when the treatment is applied and how many cures are applied. CONCLUSION: Guides introducing which concentrations of PRP are used for which diseases are to be prepared immediately by a committee which is comprised of primarily orthopedists, clinical pharmacologists and toxicologists.
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