Literature DB >> 27408431

Hypereosinophilia in a Young Patient: Occam's Razor or Hickam's Dictum?

Arjun Lakshman1, Ram V Nampoothiri1, Arjun Datt Law1, Pankaj Malhotra1, Subhash C Varma1.   

Abstract

Hypereosinophilia is an uncommon clinical problem encountered in hematology practice. While most of such cases are secondary or reactive, a significant fraction of cases are due to clonal myeloproliferative disorders. We report a young patient who presented with marked hypereosinophilia and was investigated extensively for its cause. Finally a common tropical infection was responsible for such marked eosinophilia fulfilling the principle of Occam's razor. The case emphasizes the need to search for treatable reactive causes even in presence of marked hypereosinophilia in a tropical country.

Entities:  

Keywords:  Giardiasis; Marked hypereosinophilia; Myeloproliferative disorder; Occam’s razor

Year:  2014        PMID: 27408431      PMCID: PMC4925477          DOI: 10.1007/s12288-014-0487-9

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN: 0971-4502            Impact factor:   0.900


  14 in total

1.  A patient with a mucocutaneous eruption and intestinal giardiasis.

Authors:  K Lammintausta; P Kotilainen; U Hohenthal; L Talve
Journal:  Acta Derm Venereol       Date:  2001 Aug-Sep       Impact factor: 4.437

Review 2.  Practical approach to the patient with hypereosinophilia.

Authors:  Florence Roufosse; Peter F Weller
Journal:  J Allergy Clin Immunol       Date:  2010-06-09       Impact factor: 10.793

3.  [Gastroenteritis with eosinophilia caused by Giardia lamblia].

Authors:  A Ortiz Arduan; J M Castrillo; J Carreira; L López Cubero; R Miranda; M Jiménez Casado
Journal:  Rev Clin Esp       Date:  1990-06       Impact factor: 1.556

4.  Interleukin (IL) 5 levels and eosinophilia in patients with intestinal parasitic diseases.

Authors:  Sebnem Ustun; Nevin Turgay; Songul-Bayram Delibas; Hatice Ertabaklar
Journal:  World J Gastroenterol       Date:  2004-12-15       Impact factor: 5.742

5.  A case of giardiasis expressing severe systemic symptoms and marked hypereosinophilia.

Authors:  Yuhko Suzuki; Takeshi Nakamura; Masaharu Tokoro; Tomiteru Togano; Manabu Ohsaka; Mika Kohri; Yasuyoshi Hirata; Koji Miyazaki; Mikio Danbara; Ryouichi Horie; Ikuo Miura; Keisuke Sunakawa; Masaaki Higashihara
Journal:  Parasitol Int       Date:  2010-06-23       Impact factor: 2.230

Review 6.  World Health Organization-defined eosinophilic disorders: 2014 update on diagnosis, risk stratification, and management.

Authors:  Jason Gotlib
Journal:  Am J Hematol       Date:  2014-03       Impact factor: 10.047

Review 7.  Hypereosinophilia in Acute Lymphoblastic Leukemia: Two Cases with Review of Literature.

Authors:  Kamal Kant Sahu; Pankaj Malhotra; Alka Khadwal; Manupdesh Singh Sachdeva; Prashant Sharma; Neelam Varma; Subhash Chander Varma
Journal:  Indian J Hematol Blood Transfus       Date:  2014-07-30       Impact factor: 0.900

8.  Systemic and mucosal responses to oral administration of excretory and secretory antigens from Giardia intestinalis.

Authors:  Juan Carlos Jiménez; Josette Fontaine; Jean-Marie Grzych; Eduardo Dei-Cas; Monique Capron
Journal:  Clin Diagn Lab Immunol       Date:  2004-01

Review 9.  Synovitis secondary to giardiasis in children.

Authors:  M Letts; D Davidson; F Lalonde
Journal:  Am J Orthop (Belle Mead NJ)       Date:  1998-06

10.  [Marked hematic hypereosinophilia caused by Giardia Lamblia infestation in a subject with Churg-Strauss syndrome].

Authors:  E Ferrante; S Valente; G M Corbo; C Rumi; C De Simone; G Ciappi
Journal:  Minerva Med       Date:  1991-10       Impact factor: 4.806

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