Literature DB >> 27408346

Bilateral Facial Nerve Palsy in Acute B Cell Lymphoblastic Leukemia: A Case Report and Review of the Literature.

Shiraj Sen1, Arjun Gupta1, Paul Friedman2, Harris V Naina3.   

Abstract

Acute lymphoblastic leukemia (ALL) is a haematological malignancy that can involve the central nervous system (CNS). Less than 10 % of patients with ALL have CNS involvement at presentation. The cranial nerve most commonly affected is cranial nerve VII although bilateral involvement is rare. Management and outcomes of these patients are not well understood. Moreover bilateral Bells palsy as a presenting symptom of ALL is extremely uncommon. We report a very unusual presentation of ALL with bilateral facial nerve palsy, and discuss the management strategies and outcomes for patients with ALL that present with cranial nerve palsies.

Entities:  

Keywords:  Acute lymphoblastic leukemia; Bells palsy; CNS leukemia; Whole brain irradiation

Year:  2015        PMID: 27408346      PMCID: PMC4925496          DOI: 10.1007/s12288-015-0526-1

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN: 0971-4502            Impact factor:   0.900


  29 in total

Review 1.  Bell's palsy: the spontaneous course of 2,500 peripheral facial nerve palsies of different etiologies.

Authors:  Erik Peitersen
Journal:  Acta Otolaryngol Suppl       Date:  2002

2.  Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia.

Authors:  H M Kantarjian; S O'Brien; T L Smith; J Cortes; F J Giles; M Beran; S Pierce; Y Huh; M Andreeff; C Koller; C S Ha; M J Keating; S Murphy; E J Freireich
Journal:  J Clin Oncol       Date:  2000-02       Impact factor: 44.544

3.  Precursor T cell acute lymphoblastic lymphoma presenting as bilateral facial nerve palsy.

Authors:  Nishant Tageja; Jason Valent; Gail Bentley; Jeffrey Zonder
Journal:  Chemotherapy       Date:  2010-06-16       Impact factor: 2.544

4.  Reversal of cranial nerve dysfunction with radiation therapy in adults with lymphoma and leukemia.

Authors:  J R Gray; K E Wallner
Journal:  Int J Radiat Oncol Biol Phys       Date:  1990-08       Impact factor: 7.038

Review 5.  Pediatric bilateral facial paralysis.

Authors:  V Smith; D N Traquina
Journal:  Laryngoscope       Date:  1998-04       Impact factor: 3.325

6.  Facial nerve palsy as an early manifestation of relapse in T-cell acute lymphoblastic leukemia.

Authors:  Y J Juhn; S Inoue
Journal:  Ear Nose Throat J       Date:  1996-03       Impact factor: 1.697

7.  Acute myeloid leukemia presenting as one-and-a-half syndrome.

Authors:  Wen-Hsin Hsu; Shi-Jye Chu; Wei-Chi Tsai; Yu-Tzu Tsao
Journal:  Am J Emerg Med       Date:  2008-05       Impact factor: 2.469

8.  Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis: results from the international ALL trial MRC UKALL XII/ECOG E2993.

Authors:  Hillard M Lazarus; Susan M Richards; Raj Chopra; Mark R Litzow; Alan K Burnett; Peter H Wiernik; Ian M Franklin; Martin S Tallman; Lucy Cook; Georgina Buck; I Jill Durrant; Jacob M Rowe; Anthony H Goldstone
Journal:  Blood       Date:  2006-03-23       Impact factor: 22.113

9.  Facial palsy as first presentation of acute myeloid leukemia.

Authors:  Bhrigu Raj Sood; Brij Sharma; Satish Kumar; Dalip Gupta; Ashok Sharma
Journal:  Am J Hematol       Date:  2003-11       Impact factor: 10.047

10.  Central nervous system involvement at presentation in childhood acute lymphoblastic leukemia: management experience and lessons.

Authors:  Ram K Marwaha; Ketan P Kulkarni; Deepak Bansal; Amita Trehan
Journal:  Leuk Lymphoma       Date:  2010-02
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  1 in total

Review 1.  Neoplastic nerve lesions.

Authors:  Deep K Patel; Kelly G Gwathmey
Journal:  Neurol Sci       Date:  2022-02-23       Impact factor: 3.830

  1 in total

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