Literature DB >> 27407875

Safety and Efficacy of Sodium Bicarbonate versus Hyaluronidase in Peribulbar Anaesthesia.

R P Gupta1, G Kapoor2.   

Abstract

BACKGROUND: 400 cases undergoing surgery for cataract under local anaesthesia were studied. Peribulbar anaesthesia involves injecting a mixture of 2% lignocaine, bupivicaine 0.5% and hyaluronidase into the peripheral space of the orbit through a single infero-lateral point. Sodium bicarbonate has been shown to reduce the time of onset of anaesthesia and pain perception when mixed with local anaesthetics.
METHODS: This study compared two groups of patients (200 each), one receiving hyaluronidase mixed anaesthetic and the other sodium bicarbonate buffered anaesthetic. The groups were compared for effectiveness of the anaesthesia, its onset, duration and the final visual outcome. RESULTS AND
CONCLUSION: Sodium bicarbonate was shown to reduce the time of onset and increase the successful block rate without any adverse affects.

Entities:  

Keywords:  Hyaluronidase; Peribulbar; Sodium bicarbonate

Year:  2011        PMID: 27407875      PMCID: PMC4921994          DOI: 10.1016/S0377-1237(06)80050-X

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  10 in total

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Journal:  Minerva Anestesiol       Date:  1999-11       Impact factor: 3.051

2.  Hyaluronidase in epidural analgesia.

Authors:  D B SCOTT
Journal:  Br J Anaesth       Date:  1956-04       Impact factor: 9.166

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Authors:  J E ECKENHOFF; C K KIRBY
Journal:  Anesthesiology       Date:  1951-01       Impact factor: 7.892

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Authors:  G A Dempsey; P J Barrett; I J Kirby
Journal:  Br J Anaesth       Date:  1997-06       Impact factor: 9.166

5.  Sodium bicarbonate attenuates pain on skin infiltration with lidocaine, with or without epinephrine.

Authors:  W McKay; R Morris; P Mushlin
Journal:  Anesth Analg       Date:  1987-06       Impact factor: 5.108

6.  Value of hyaluronidase in ocular surgical akinesia.

Authors:  J S Mindel
Journal:  Am J Ophthalmol       Date:  1978-05       Impact factor: 5.258

7.  Peribulbar anesthesia. Effect of bicarbonate on mixtures of lidocaine, bupivacaine, and hyaluronidase with or without epinephrine.

Authors:  K Zahl; A Jordan; J McGroarty; B Sorensen; A W Gotta
Journal:  Ophthalmology       Date:  1991-02       Impact factor: 12.079

8.  Sub-Tenon's local anaesthesia: the effect of hyaluronidase.

Authors:  S A Rowley; J E Hale; R D Finlay
Journal:  Br J Ophthalmol       Date:  2000-04       Impact factor: 4.638

9.  Sodium bicarbonate--an alternative to hyaluronidase in ocular anaesthesia for cataract surgery.

Authors:  M Srinivasan; M Vamshidhar; R Gopal
Journal:  Indian J Ophthalmol       Date:  2000-12       Impact factor: 1.848

10.  Re-evaluation of hyaluronidase in peribulbar anaesthesia.

Authors:  D P Prosser; G E Rodney; T Mian; H M Jones; M Y Khan
Journal:  Br J Ophthalmol       Date:  1996-09       Impact factor: 4.638

  10 in total
  2 in total

1.  Combating inadequate anesthesia in periapical infections, with sodium bicarbonate: a clinical double blind study.

Authors:  Savina Gupta; Geetanjali Mandlik; Mukul N Padhye; Yogesh K Kini; Shruti Kakkar; Abhinav Vijay Hire
Journal:  Oral Maxillofac Surg       Date:  2013-06-06

2.  A Comparative Study of Sodium Bicarbonate and Hyaluronidase on Pain Perception, Anesthesia, and Akinesia during Peribulbar Anesthesia for Cataract Surgery.

Authors:  Priyanka Sodani; Sandeepika Dogra; Dev Raj; Vabita Bhagat
Journal:  Anesth Essays Res       Date:  2022-05-31
  2 in total

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