S S Anand1, R K Handa2, Jogender Singh3, I Sinha4. 1. Sr Adv (Nuclear Medicine), AH (R&R), New Delhi. 2. Classified Specialist (Paediatric Surg), CH (EC) Kolkata. 3. Scientist -E, CH (EC), Kolkata. 4. Classified Specialist (Radiology), CH (EC), Kolkata.
Abstract
BACKGROUND: Biliary Atresia and Neonatal Hepatitis are the two major causes of Persistent Neonatal Jaundice. Differentiation is done by biochemical and radiological tests. Radiological investigations use intra-or extra-hepatic biliary dilation for diagnosing biliary atresia but this is not always reliable. METHODS: 14 neonates with persistent conjugated hyperbilirubinemia who had undergone hepato-biliary scintigraphy were retrospectively evaluated and those having Extrahepatic Biliary Atresia were analyzed with reference to operative findings. RESULTS: 11 out of 14 had Extrahepatic Biliary Atresia during operation whereas 3 proved to be false positive. CONCLUSION: Mebrofenin hepato - biliary scintigraphy is a simple, safe, accurate and cost effective investigation for diagnosis of biliary atresia.
BACKGROUND:Biliary Atresia and Neonatal Hepatitis are the two major causes of Persistent Neonatal Jaundice. Differentiation is done by biochemical and radiological tests. Radiological investigations use intra-or extra-hepatic biliary dilation for diagnosing biliary atresia but this is not always reliable. METHODS: 14 neonates with persistent conjugated hyperbilirubinemia who had undergone hepato-biliary scintigraphy were retrospectively evaluated and those having Extrahepatic Biliary Atresia were analyzed with reference to operative findings. RESULTS: 11 out of 14 had Extrahepatic Biliary Atresia during operation whereas 3 proved to be false positive. CONCLUSION: Mebrofenin hepato - biliary scintigraphy is a simple, safe, accurate and cost effective investigation for diagnosis of biliary atresia.
Authors: R A Nagel; D Westaby; A Javaid; J Kavani; H B Meire; M G Lombard; A Wise; R Williams; M E Hodson Journal: Lancet Date: 1989-12-16 Impact factor: 79.321
Authors: K L Cox; R C Stadalnik; J P McGahan; K Sanders; R A Cannon; B H Ruebner Journal: J Pediatr Gastroenterol Nutr Date: 1987 Nov-Dec Impact factor: 2.839