Literature DB >> 27407834

Misoprostol as aid in First Trimester MTP.

Shakti Vardhan1, R C Behera2, G S Sandhu1, B K Goyal3.   

Abstract

BACKGROUND: Medical Termination of Pregnancy (MTP) is a commonly performed during the first trimester. Dilatation and Evacuation (D & E) mandates rapid dilatation of cervix with metal dilators, which requires anaesthesia and may be associated with trauma to the uterus, cervix and later cervical incompetence. The problem of rapid cervical dilatation is obviated with intravaginal misoprostol.
METHODS: Intravaginal misoprostol tablet 200 microgram was inserted, a night prior to MTP to ripen the cervix. Cervix was dilated with metal dilators only in cases where cervix did not loosen up sufficiently. Products of conception were removed by suction.
RESULTS: Out of 108 cases cervical dilatation was not required in 96 cases (88.9%).
CONCLUSION: Intravaginal misoprostol 200 microgram proved effective as a priming agent prior to MTP in the first trimester.

Entities:  

Keywords:  MTP; Misoprostol

Year:  2011        PMID: 27407834      PMCID: PMC4923270          DOI: 10.1016/S0377-1237(06)80144-9

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  10 in total

1.  Side effects of mifepristone-misoprostol abortion versus surgical abortion. Data from a trial in China, Cuba, and India.

Authors:  B Elul; C Ellertson; B Winikoff; K Coyaji
Journal:  Contraception       Date:  1999-02       Impact factor: 3.375

2.  Uterine contractility and induction of abortion in early pregnancy by misoprostol and mifepristone.

Authors:  J E Norman; K J Thong; D T Baird
Journal:  Lancet       Date:  1991-11-16       Impact factor: 79.321

3.  Early pregnancy termination with mifepristone and misoprostol in the United States.

Authors:  I M Spitz; C W Bardin; L Benton; A Robbins
Journal:  N Engl J Med       Date:  1998-04-30       Impact factor: 91.245

4.  A comparative study of surgical and medical procedures: 932 pregnancy terminations up to 63 days gestation.

Authors:  T J Child; J Thomas; M Rees; I Z MacKenzie
Journal:  Hum Reprod       Date:  2001-01       Impact factor: 6.918

Review 5.  Medical abortion in early pregnancy: a review of the evidence.

Authors:  D A Grimes
Journal:  Obstet Gynecol       Date:  1997-05       Impact factor: 7.661

6.  Efficacy of mifepristone followed on the same day by misoprostol for early termination of pregnancy: report of a randomised trial.

Authors:  M D Creinin; J L Schwartz; H C Pymar; W Fink
Journal:  BJOG       Date:  2001-05       Impact factor: 6.531

7.  Misoprostol alone--a new method of medical abortion?

Authors:  K Blanchard; B Winikoff; K Coyaji; T N Nguyen
Journal:  J Am Med Womens Assoc (1972)       Date:  2000

8.  Mifepristone followed on the same day by vaginal misoprostol for early abortion.

Authors:  H C Pymar; M D Creinin; J L Schwartz
Journal:  Contraception       Date:  2001-08       Impact factor: 3.375

Review 9.  Mifepristone (RU 486)--a modulator of progestin and glucocorticoid action.

Authors:  I M Spitz; C W Bardin
Journal:  N Engl J Med       Date:  1993-08-05       Impact factor: 91.245

10.  Early termination of pregnancy with mifepristone (RU 486) and the orally active prostaglandin misoprostol.

Authors:  R Peyron; E Aubény; V Targosz; L Silvestre; M Renault; F Elkik; P Leclerc; A Ulmann; E E Baulieu
Journal:  N Engl J Med       Date:  1993-05-27       Impact factor: 91.245

  10 in total

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