M S Barthwal1, K E Rajan2, R B Deoskar3, S K Sharma4. 1. Classified Specialist(Medicine) MH Namkum. 2. Senior Advisor(Medicine and Respiratory Medicine), Military Hospital (CTC), Pune-40. 3. Classified Specialist(Medicine) MH Namkum; Classified Specialist (Med) BH Delhi Cantt. 4. Commandant, Military Hospital (CTC), Pune-40.
Abstract
BACKGROUND: In view of increase in incidence of exptrapulmonary tuberculosis after the epidemic of human immunodeficiency virus infection, the clinical profile of extrapulmonary tuberculosis in patients with HIV infection was studied. METHOD: The study population comprised patients of HIV infection with extrapulmonary tuberculosis. Work up included history, clinical examination, sputum for acid fast bacilli, chext X-ray, ultrasonography (USG) abdomen, fine needle aspiration cytology(FNAC), transbronchial needle aspiration (TBNA) and computed tomography of chest. RESULTS: There were 50 cases, all males with mean age of 35 years. 24(48%) were without pulmonary tuberculosis and 26(52%) had pulmonary tuberculosis. 41(82%) had disseminated disease and 9(18%) involve one site. Fever and weight loss were the most frequent symptoms (79% and 58% respectively) in cases without pulmonary tuberculosis. The most frequent extrapulmonary site was lymph node in 46(92%), followed by spleen in 13(26%), pleura 9(18%), miliary 7(14%) and hepatic 1(2%). The diagnosis was confirmed by invasive methods in 30 out of 50(60%) cases [FNAC in 23(88%), TBNA in 2(25%) and pleural biopsy in 5(55%)]. CONCLUSION: In HIV infected patients, the most common extrapulmonary site is lymph mode followed by spleen.
BACKGROUND: In view of increase in incidence of exptrapulmonary tuberculosis after the epidemic of human immunodeficiency virus infection, the clinical profile of extrapulmonary tuberculosis in patients with HIV infection was studied. METHOD: The study population comprised patients of HIV infection with extrapulmonary tuberculosis. Work up included history, clinical examination, sputum for acid fast bacilli, chext X-ray, ultrasonography (USG) abdomen, fine needle aspiration cytology(FNAC), transbronchial needle aspiration (TBNA) and computed tomography of chest. RESULTS: There were 50 cases, all males with mean age of 35 years. 24(48%) were without pulmonary tuberculosis and 26(52%) had pulmonary tuberculosis. 41(82%) had disseminated disease and 9(18%) involve one site. Fever and weight loss were the most frequent symptoms (79% and 58% respectively) in cases without pulmonary tuberculosis. The most frequent extrapulmonary site was lymph node in 46(92%), followed by spleen in 13(26%), pleura 9(18%), miliary 7(14%) and hepatic 1(2%). The diagnosis was confirmed by invasive methods in 30 out of 50(60%) cases [FNAC in 23(88%), TBNA in 2(25%) and pleural biopsy in 5(55%)]. CONCLUSION: In HIV infectedpatients, the most common extrapulmonary site is lymph mode followed by spleen.
Authors: A González-López; F Dronda; M Alonso-Sanz; F Chaves; I Fernández-Martin; L López-Cubero Journal: Clin Infect Dis Date: 1997-06 Impact factor: 9.079
Authors: A Porcel-Martin; P Rendon-Unceta; A Bascuñana-Quirell; A Amaya-Vidal; C Rodriguez-Ramos; M J Soria de la Cruz; L Martín-Herrera Journal: Abdom Imaging Date: 1998 Mar-Apr