Literature DB >> 27407763

Mode of Detection of HIV Infection - A Retrospective Study of 612 Cases.

Y K Sharma1, S K Sayal2.   

Abstract

BACKGROUND: Trends in mode of detection of HIV infection in the Armed Forces required to be analyzed to formulate future strategies for early detection.
METHODS: A retrospective study was thus conducted in 612 newly diagnosed HIV-positive cases between January 1997 to August 2002.
RESULTS: 182(29.74%) patients had already developed Category C conditions when detected to be HIV-positive, 176(96.70%) with mycobacterial disease, majority (67.61%) of them being pulmonary tuberculosis, followed by recurrent bacterial pneumonia in 3 (1.65%), pneumocystis carinii pneumonia (PCP) in 2(1.1%) and oesophageal candidiasis in one (0.55%). Herpes zoster was the third most common mode of detection accounting for 86 (14.05%) of the cases (24.6% of them with involvement of ophthalmic branch of trigeminal nerve), after tuberculosis in 176(28.76%) and blood donors in 98(16.01%), followed by constitutional symptoms in 59(9.64%) cases, investigation for STDs in 56(9.15%), bacterial pneumonia in 6(0.98%) and oral mucosal candidiasis in only one (0.16%) case. None was detected during acute retroviral illness and only 5(0.82%) cases were detected while being investigated for generalized lymphadenopathy. Amongst the cases detected during investigation for STDs, majority (26.79%) were on STD surveillance. 22(3.60%) cases tested positive when their spouses were detected to be HIV-positive, 20(3.27%) while being screened for surgery, 4(0.65%) for posting abroad and 2(0.32%) each during investigation when child was found HIV-positive and investigation for HBV infection. Remaining 69(11.27%) patients were detected during investigation of various related or unrelated conditions including one (0.16%), which reported voluntarily after a high-risk exposure.
CONCLUSION: There is a need to encourage voluntary reporting and identify more number of cases during acute retroviral syndrome and PGL stage.

Entities:  

Keywords:  HIV infection; Mode of detection

Year:  2011        PMID: 27407763      PMCID: PMC4925644          DOI: 10.1016/S0377-1237(05)80157-1

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


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