Literature DB >> 27407568

Acinetobacter spp as Nosocomial Pathogen : Clinical Significance and Antimicrobial Sensitivity.

K K Lahiri1, N S Mani2, S S Purai3.   

Abstract

Acinetobacter spp are ubiquitous aerobic Gram negative coccobacillus, that are now increasingly responsible for a large number of nosocomial infections. In our study, over a period of six months (Jan-Jun 2000) at a tertiary care hospital, 152 (12.9%) isolates of Acinetobacter spp were obtained from a total of 1175 isolates grown from all clinical specimens. Most of the isolates 126 (82.9%) were from hospitalised patients in the spinal cord injury centre, intensive care units and those on prior antibiotic therapy. Community acquired infections were also seen in 26 (17.1%) out patient department (OPD) cases. Isolates were from urine, respiratory exudates, blood and pus/burn wound swabs predominantly. They were resistant to commonly used antibiotics while being sensitive to amikacin, augmentin, piperacillin, netilmicin and cefotaxime. 69.2% isolates exhibited resistance to two or more antibiotics. Clinical co-relation must be under taken to exclude commensal contaminants, before considering it to be a pathogen and prescribing antibiotics to the patient.

Entities:  

Keywords:  Acinetobacter spp; Antibiotic resistance; Nosocomial infection

Year:  2011        PMID: 27407568      PMCID: PMC4923491          DOI: 10.1016/S0377-1237(04)80148-5

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  8 in total

1.  Acinetobacter baumannii infections in the ICU: customization is the key.

Authors:  J Rello
Journal:  Chest       Date:  1999-05       Impact factor: 9.410

Review 2.  Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features.

Authors:  E Bergogne-Bérézin; K J Towner
Journal:  Clin Microbiol Rev       Date:  1996-04       Impact factor: 26.132

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Authors:  K J Towner
Journal:  J Med Microbiol       Date:  1997-09       Impact factor: 2.472

4.  Characterization of a hospital outbreak of imipenem-resistant Acinetobacter baumannii by phenotypic and genotypic typing methods.

Authors:  J Tankovic; P Legrand; G De Gatines; V Chemineau; C Brun-Buisson; J Duval
Journal:  J Clin Microbiol       Date:  1994-11       Impact factor: 5.948

5.  Risk factors for an outbreak of multi-drug-resistant Acinetobacter nosocomial pneumonia among intubated patients.

Authors:  R N Husni; L S Goldstein; A C Arroliga; G S Hall; C Fatica; J K Stoller; S M Gordon
Journal:  Chest       Date:  1999-05       Impact factor: 9.410

6.  Simplified phenotypic tests for identification of Acinetobacter spp. and their antimicrobial susceptibility status.

Authors:  K Prashanth; S Badrinath
Journal:  J Med Microbiol       Date:  2000-09       Impact factor: 2.472

7.  Nosocomial Acinetobacter baumannii infections: microbiological and clinical epidemiology.

Authors:  D Villers; E Espaze; M Coste-Burel; F Giauffret; E Ninin; F Nicolas; H Richet
Journal:  Ann Intern Med       Date:  1998-08-01       Impact factor: 25.391

8.  Infections with Acinetobacter calcoaceticus (Herellea vaginicola): clinical and laboratory studies.

Authors:  R H Glew; R C Moellering; L J Kunz
Journal:  Medicine (Baltimore)       Date:  1977-03       Impact factor: 1.889

  8 in total
  1 in total

1.  Acinetobacter spp as emerging pathogen in neonatal septicemia.

Authors:  Madhu Sharma; Sarita Yadav; Uma Chaudhary
Journal:  Indian J Pediatr       Date:  2009-08       Impact factor: 1.967

  1 in total

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