| Literature DB >> 27406341 |
Antoine Fruleux1, Rhoda J Hawkins.
Abstract
Cell migration is important for the function of many eukaryotic cells. Recently the nucleus has been shown to play an important role in cell motility. After giving an overview of cell motility mechanisms we review what is currently known about the mechanical properties of the nucleus and the connections between it and the cytoskeleton. We also discuss connections to the extracellular matrix and mechanotransduction. We identify key physical roles of the nucleus in cell migration.Mesh:
Year: 2016 PMID: 27406341 DOI: 10.1088/0953-8984/28/36/363002
Source DB: PubMed Journal: J Phys Condens Matter ISSN: 0953-8984 Impact factor: 2.333