Literature DB >> 27402612

Implications of Small Samples for Generalization: Adjustments and Rules of Thumb.

Elizabeth Tipton1, Kelly Hallberg2, Larry V Hedges3, Wendy Chan4.   

Abstract

BACKGROUND: Policy makers and researchers are frequently interested in understanding how effective a particular intervention may be for a specific population. One approach is to assess the degree of similarity between the sample in an experiment and the population. Another approach is to combine information from the experiment and the population to estimate the population average treatment effect (PATE).
METHOD: Several methods for assessing the similarity between a sample and population currently exist as well as methods estimating the PATE. In this article, we investigate properties of six of these methods and statistics in the small sample sizes common in education research (i.e., 10-70 sites), evaluating the utility of rules of thumb developed from observational studies in the generalization case. RESULT: In small random samples, large differences between the sample and population can arise simply by chance and many of the statistics commonly used in generalization are a function of both sample size and the number of covariates being compared. The rules of thumb developed in observational studies (which are commonly applied in generalization) are much too conservative given the small sample sizes found in generalization.
CONCLUSION: This article implies that sharp inferences to large populations from small experiments are difficult even with probability sampling. Features of random samples should be kept in mind when evaluating the extent to which results from experiments conducted on nonrandom samples might generalize.

Keywords:  content area; education; methodological development

Mesh:

Year:  2016        PMID: 27402612     DOI: 10.1177/0193841X16655665

Source DB:  PubMed          Journal:  Eval Rev        ISSN: 0193-841X


  9 in total

1.  Generalizing Treatment Effect Estimates From Sample to Population: A Case Study in the Difficulties of Finding Sufficient Data.

Authors:  Elizabeth A Stuart; Anna Rhodes
Journal:  Eval Rev       Date:  2016-08-04

2.  Estimation of Population Average Treatment Effects in the FIRST Trial: Application of a Propensity Score-Based Stratification Approach.

Authors:  Jeanette W Chung; Karl Y Bilimoria; Jonah J Stulberg; Christopher M Quinn; Larry V Hedges
Journal:  Health Serv Res       Date:  2017-08-21       Impact factor: 3.402

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Journal:  Brain Sci       Date:  2022-05-31

4.  Assessing the Influence of Food Insecurity and Retail Environments as a Proxy for Structural Racism on the COVID-19 Pandemic in an Urban Setting.

Authors:  Rachael D Dombrowski; Alex B Hill; Bree Bode; Kathryn A G Knoff; Hadis Dastgerdizad; Noel Kulik; James Mallare; Kibibi Blount-Dorn; Winona Bynum
Journal:  Nutrients       Date:  2022-05-20       Impact factor: 6.706

5.  A Retrospective Naturalistic Study Comparing the Efficacy of Ketamine and Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Depression.

Authors:  Georgios Mikellides; Panayiota Michael; Lilia Psalta; Teresa Schuhmann; Alexander T Sack
Journal:  Front Psychiatry       Date:  2022-01-13       Impact factor: 4.157

6.  Efficacy of a Communication-Priming Intervention on Documented Goals-of-Care Discussions in Hospitalized Patients With Serious Illness: A Randomized Clinical Trial.

Authors:  Robert Y Lee; Erin K Kross; Lois Downey; Sudiptho R Paul; Joanna Heywood; Elizabeth L Nielsen; Kelson Okimoto; Lyndia C Brumback; Susan E Merel; Ruth A Engelberg; J Randall Curtis
Journal:  JAMA Netw Open       Date:  2022-04-01

7.  Two-stage matching-adjusted indirect comparison.

Authors:  Antonio Remiro-Azócar
Journal:  BMC Med Res Methodol       Date:  2022-08-08       Impact factor: 4.612

8.  Understanding the association between adverse childhood experiences and subsequent attention deficit hyperactivity disorder: A systematic review and meta-analysis of observational studies.

Authors:  Ning Zhang; Man Gao; Jinglong Yu; Qiang Zhang; Weiguang Wang; Congxiao Zhou; Lingjia Liu; Ting Sun; Xing Liao; Junhong Wang
Journal:  Brain Behav       Date:  2022-09-06       Impact factor: 3.405

9.  Detecting neonatal acute bilirubin encephalopathy based on T1-weighted MRI images and learning-based approaches.

Authors:  Miao Wu; Xiaoxia Shen; Can Lai; Weihao Zheng; Yingqun Li; Zhongli Shangguan; Chuanbo Yan; Tingting Liu; Dan Wu
Journal:  BMC Med Imaging       Date:  2021-06-22       Impact factor: 1.930

  9 in total

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