Islam H Metwally1, Amr F Elalfy2, Shadi Awny2, Islam A Elzahaby2, Reham M Abdelghani3. 1. Surgical Oncology Unit, Oncology Center Mansoura University (OCMU), Mansoura, Egypt. Electronic address: drislamhany@mans.edu.eg. 2. Surgical Oncology Unit, Oncology Center Mansoura University (OCMU), Mansoura, Egypt. 3. Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Abstract
OBJECTIVES: This study aims at reporting 2 cases of primary ovarian carcinoid tumor, and providing an adequate registry of such cases and how they were managed. METHODS: 2 female patients with primary ovarian carcinoid were diagnosed and treated in our center. Discussion of their presentation, pathology and treatment is entitled. Also a thorough search of all published registries and case reports of ovarian carcinoid was done with analysis of reported data. RESULTS: 164 cases of primary ovarian carcinoid tumor were detected since 2005 with the predominance of the insular variant. Carcinoid syndrome occurs in nearly 14% of these cases. Most of the cases were treated with hysterectomy. Unfortunately, the prognosis was not documented in most series. CONCLUSION: Primary ovarian carcinoid is a relatively rare disease with an indolent course and excellent outcome. Carcinoid syndrome, especially carcinoid heart disease may worsen the prognosis. Total abdominal hysterectomy with bilateral salpingo-oophorectomy has been commonly used as the treatment of choice of primary ovarian carcinoid tumors.
OBJECTIVES: This study aims at reporting 2 cases of primary ovarian carcinoid tumor, and providing an adequate registry of such cases and how they were managed. METHODS: 2 female patients with primary ovarian carcinoid were diagnosed and treated in our center. Discussion of their presentation, pathology and treatment is entitled. Also a thorough search of all published registries and case reports of ovarian carcinoid was done with analysis of reported data. RESULTS: 164 cases of primary ovarian carcinoid tumor were detected since 2005 with the predominance of the insular variant. Carcinoid syndrome occurs in nearly 14% of these cases. Most of the cases were treated with hysterectomy. Unfortunately, the prognosis was not documented in most series. CONCLUSION:Primary ovarian carcinoid is a relatively rare disease with an indolent course and excellent outcome. Carcinoid syndrome, especially carcinoid heart disease may worsen the prognosis. Total abdominal hysterectomy with bilateral salpingo-oophorectomy has been commonly used as the treatment of choice of primary ovarian carcinoid tumors.
Authors: Marta Opalińska; Anna Sowa-Staszczak; Helena Olearska; Magdalena Ulatowska-Bialas; Aleksandra Gilis-Januszewska; Alicja Hubalewska-Dydejczyk Journal: Front Endocrinol (Lausanne) Date: 2021-11-30 Impact factor: 5.555