Literature DB >> 27401014

Body Composition and Bone Mineral Density in Patients With Heart Failure.

Demetrius A Abshire1, Debra K Moser2, Jody L Clasey3, Misook L Chung2, Susan J Pressler4, Sandra B Dunbar5, Seongkum Heo6, Terry A Lennie2.   

Abstract

The purpose of this study was to examine associations among bone mineral density, osteopenia/osteoporosis, body mass index (BMI), and body composition in patients with heart failure (HF). A total of 119 patients (age = 61 ± 12 years, 65% male) underwent dual-energy X-ray absorptiometry scans to determine bone mineral density and body composition. In multivariable linear regressions, BMI, relative skeletal muscle index (RSMI), and mineral-free lean mass were positively associated with total body bone mineral density. Mineral-free lean mass was most strongly associated with bone mineral density (β = .398). In multivariable logistic regressions, higher BMI, RSMI, and mineral-free lean mass were associated with lower odds for osteopenia/osteoporosis. Fat mass was not associated with total body bone mineral density or osteopenia/osteoporosis. These results suggest that muscle mass may be the important component of body mass associated with bone mineral density in patients with HF.

Entities:  

Keywords:  bone mineral density; heart failure; obesity; sarcopenia

Mesh:

Year:  2016        PMID: 27401014      PMCID: PMC5225244          DOI: 10.1177/0193945916658885

Source DB:  PubMed          Journal:  West J Nurs Res        ISSN: 0193-9459            Impact factor:   1.967


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