Literature DB >> 27400132

Acceptorless Dehydrogenative Cyclization of o-Aminobenzyl Alcohols with Ketones to Quinolines in Water Catalyzed by Water-Soluble Metal-Ligand Bifunctional Catalyst [Cp*(6,6'-(OH)2bpy)(H2O)][OTf]2.

Rongzhou Wang1, Hongjun Fan1, Wei Zhao1, Feng Li1,2.   

Abstract

The strategy for acceptorless dehydrogenative cyclization of o-aminobenzyl alcohols with ketones to quinolines in water has been accomplished. In the presence of [Cp*Ir(6,6'-(OH)2bpy)(H2O)][OTf]2, a series of desirable products were obtained in high yields. Notably, this research exhibits the potential for the construction of heterocycles via acceptorless dehydrogenative reactions in water catalyzed by water-soluble metal-ligand bifunctional catalysts.

Entities:  

Year:  2016        PMID： 27400132     DOI： 10.1021/acs.orglett.6b01518

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  N-Heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using DMSO as an oxidant at room temperature.

Authors:  Jingxiu Xu; Qingmao Chen; Zhigao Luo; Xiaodong Tang; Jinwu Zhao
Journal:  RSC Adv       Date:  2019-09-12       Impact factor: 4.036

2.  Ruthenium Complexes Bearing α-Diimine Ligands and Their Catalytic Applications in N-Alkylation of Amines, α-Alkylation of Ketones, and β-Alkylation of Secondary Alcohols.

Authors:  Sekar Gayathri; Periasamy Viswanathamurthi; Roberta Bertani; Paolo Sgarbossa
Journal:  ACS Omega       Date:  2022-09-07

3.  Transition-metal-free approach to quinolines via direct oxidative cyclocondensation reaction of N,N-dimethyl enaminones with o-aminobenzyl alcohols.

Authors:  Kairui Rao; Zhangmengjie Chai; Pan Zhou; Donghan Liu; Yulin Sun; Fuchao Yu
Journal:  Front Chem       Date:  2022-09-21       Impact factor: 5.545
  3 in total

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