Literature DB >> 27396987

Viability of Lucilia sericata maggots after exposure to wound antiseptics.

Georg Daeschlein1, Matthias Napp2, Ojan Assadian3, Sebastian von Podewils1, Kevin Reese2, Peter Hinz2, Johannes Matiasek4, Romy Spitzmueller2, Paul Humphreys3, Michael Jünger1, Axel Kramer5.   

Abstract

After debridement and before dressing a wound with maggots of calliphorid flies, one frequently performed step is the application of antiseptics to the prepared wound bed. However, the concomitant application of antiseptic agents during maggot therapy is regarded controversial as antiseptics may interfere with maggots' viability. In this experimental in vitro study, the viability of fly maggots was investigated after exposure to various antiseptics frequently used in wound care. Here, we show that Lucilia sericata fly maggots can survive up to an hour's exposure to wound antiseptics such as octenidine, povidone-iodine or polihexanide. Concomitant short-term application of wound antiseptics together with maggots on wound beds is tolerated by larvae and does not impair their viability.
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Entities:  

Keywords:  Antisepsis; Bacterial ingestion; Bio-surgery; Disinfection; Lucilia sericata; Maggot therapy; Mobility; Wound care

Mesh:

Substances:

Year:  2016        PMID: 27396987      PMCID: PMC7949785          DOI: 10.1111/iwj.12637

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  13 in total

1.  The classic: The treatment of chronic osteomyelitis with the maggot (larva of the blow fly). 1931.

Authors:  William S Baer
Journal:  Clin Orthop Relat Res       Date:  2011-04       Impact factor: 4.176

2.  The biosurgical wound debridement: experimental investigation of efficiency and practicability.

Authors:  Felix A S Blake; Norbert Abromeit; Michael Bubenheim; Lei Li; Rainer Schmelzle
Journal:  Wound Repair Regen       Date:  2007 Sep-Oct       Impact factor: 3.617

3.  Growth effects of Phaenicia sericata larval extracts on fibroblasts: mechanism for wound healing by maggot therapy.

Authors:  P E Prete
Journal:  Life Sci       Date:  1997       Impact factor: 5.037

4.  Effectiveness of wound cleansing treatments on maggot (Diptera, Calliphoridae) mortality.

Authors:  Mollie D McIntosh; Richard W Merritt; Rebecca E Kolar; Ryan K Kimbirauskas
Journal:  Forensic Sci Int       Date:  2011-03-05       Impact factor: 2.395

Review 5.  Maggot therapy: a review of the therapeutic applications of fly larvae in human medicine, especially for treating osteomyelitis.

Authors:  R A Sherman; E A Pechter
Journal:  Med Vet Entomol       Date:  1988-07       Impact factor: 2.739

6.  Maggot therapy for the treatment of intractable wounds.

Authors:  K Y Mumcuoglu; A Ingber; L Gilead; J Stessman; R Friedmann; H Schulman; H Bichucher; I Ioffe-Uspensky; J Miller; R Galun; I Raz
Journal:  Int J Dermatol       Date:  1999-08       Impact factor: 2.736

7.  Detection and partial characterisation of two antibacterial factors from the excretions/secretions of the medicinal maggot Lucilia sericata and their activity against methicillin-resistant Staphylococcus aureus (MRSA).

Authors:  Alyson Bexfield; Yamni Nigam; Stephen Thomas; Norman A Ratcliffe
Journal:  Microbes Infect       Date:  2004-11       Impact factor: 2.700

8.  In vitro antibacterial activity of Lucilia sericata maggot secretions.

Authors:  G Daeschlein; K Y Mumcuoglu; O Assadian; B Hoffmeister; A Kramer
Journal:  Skin Pharmacol Physiol       Date:  2006-12-13       Impact factor: 3.479

9.  Maggot versus conservative debridement therapy for the treatment of pressure ulcers.

Authors:  Ronald A Sherman
Journal:  Wound Repair Regen       Date:  2002 Jul-Aug       Impact factor: 3.617

10.  Larval therapy for leg ulcers (VenUS II): randomised controlled trial.

Authors:  Jo C Dumville; Gill Worthy; J Martin Bland; Nicky Cullum; Christopher Dowson; Cynthia Iglesias; Joanne L Mitchell; E Andrea Nelson; Marta O Soares; David J Torgerson
Journal:  BMJ       Date:  2009-03-19
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  1 in total

Review 1.  Effectiveness of Chronic Wound Debridement with the Use of Larvae of Lucilia Sericata.

Authors:  Dariusz Bazaliński; Maria Kózka; Magdalena Karnas; Paweł Więch
Journal:  J Clin Med       Date:  2019-11-02       Impact factor: 4.241

  1 in total

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