| Literature DB >> 27396881 |
Y Todoroki1, S Nakano1, S Arai1, N Hirai1, H Ohigashi1.
Abstract
8'-Methylene- and 8'-methylidyneabscisic acids which might act as suicide inhibitors of the 8'-hydroxylase of abscisic acid, were designed, synthesized, and optically resolved. The (+)-isomers showed stronger inhibitory activity in rice elongation and in lettuce seed germination than (+)-abscisic acid. The activity of (+)-8'-methylidyneabscisic acid was the strongest of the analogues synthesized to date, 40-fold stronger than abscisic acid.Entities:
Keywords: 8′-methyleneabscisic acid; 8′-methylidyneabscisic acid; abscisic acid; cytochrome P-450 monooxygenase; suicide inhibitor
Year: 1997 PMID： 27396881 DOI： 10.1271/bbb.61.2043
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043