Literature DB >> 27394962

Cancer control potential of marine natural product scaffolds through inhibition of tumor cell migration and invasion.

Mudit Mudit1, Khalid A El Sayed2.   

Abstract

The marine environment is a reliable source for the discovery of novel treatment options for numerous diseases. Past research efforts toward the discovery of marine-derived anticancer agents have resulted in several commercially available marine-based drugs. The pharmaceutical value of anticancer drugs from marine natural products (MNPs) ranges from US$563 billion to US$5.69 trillion. In this review, we highlight several marine-derived entities with the potential for cancer control and prevention through the inhibition of crucial tumor cell motility and/or migration steps involved in subsequent cancer metastases. This report also covers the major hurdles typically faced by the MNPs research scientific community.
Copyright © 2016 Elsevier Ltd. All rights reserved.

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Year:  2016        PMID: 27394962     DOI: 10.1016/j.drudis.2016.06.032

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  6 in total

Review 1.  Bioactive Compounds from Marine Heterobranchs.

Authors:  Conxita Avila; Carlos Angulo-Preckler
Journal:  Mar Drugs       Date:  2020-12-21       Impact factor: 5.118

Review 2.  An Updated Review on Marine Anticancer Compounds: The Use of Virtual Screening for the Discovery of Small-Molecule Cancer Drugs.

Authors:  Verónica Ruiz-Torres; Jose Antonio Encinar; María Herranz-López; Almudena Pérez-Sánchez; Vicente Galiano; Enrique Barrajón-Catalán; Vicente Micol
Journal:  Molecules       Date:  2017-06-23       Impact factor: 4.411

3.  SP600125 enhances C-2-induced cell death by the switch from autophagy to apoptosis in bladder cancer cells.

Authors:  Haiyang Yu; Chun-Li Wu; Xiangyu Wang; Qianhong Ban; Chunhua Quan; Mengbo Liu; Hangqi Dong; Jinfeng Li; Gi-Young Kim; Yung Hyun Choi; Zhenya Wang; Cheng-Yun Jin
Journal:  J Exp Clin Cancer Res       Date:  2019-11-04

4.  Total Synthesis of Marine Alkaloids Motuporamines A and B via Ring Expansion of Cyclic β-Keto Esters.

Authors:  Zi-Jie Song; Shu-Yu Meng; Quan-Rui Wang
Journal:  ACS Omega       Date:  2020-12-22

5.  Anemonia sulcata and Its Symbiont Symbiodinium as a Source of Anti-Tumor and Anti-Oxoxidant Compounds for Colon Cancer Therapy: A Preliminary in Vitro Study.

Authors:  Laura Cabeza; Mercedes Peña; Rosario Martínez; Cristina Mesas; Milagros Galisteo; Gloria Perazzoli; Jose Prados; Jesús M Porres; Consolación Melguizo
Journal:  Biology (Basel)       Date:  2021-02-08

Review 6.  Review of Chromatographic Bioanalytical Assays for the Quantitative Determination of Marine-Derived Drugs for Cancer Treatment.

Authors:  Lotte van Andel; Hilde Rosing; Jan Hm Schellens; Jos H Beijnen
Journal:  Mar Drugs       Date:  2018-07-23       Impact factor: 5.118

  6 in total

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