| Literature DB >> 27393602 |
Federica Di Profio1, Irene Melegari1, Vittorio Sarchese1, Serena Robetto2, Giuseppe Marruchella1, Maria Cristina Bona2, Riccardo Orusa2, Vito Martella3, Fulvio Marsilio1, Barbara Di Martino4.
Abstract
Hepatitis E virus (HEV) was detected in stools collected from wild boars in Italy, with an overall prevalence of 1.5 % (3/196). The sequence of a ~3.0-kb portion at the 3' end of the genome of one such strain, HEV/WB/P6-15/ITA, was determined. In the full-length ORF2, which encodes the capsid protein, the virus was genetically closest to wild boar and human HEV strains currently classified as genotype 3 subtype c. Interestingly, the 3' end of ORF2 of the WB/P6-15/ITA matched the 340-nucleotide (nt) sequence (94.0 % nt identity) of the human strain PeGe, identified in 2015 from a patient with acute hepatitis E in Genoa, Italy, suggesting that similar HEV strains are circulating in the same geographical setting in humans and animals.Entities:
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Year: 2016 PMID： 27393602 DOI： 10.1007/s00705-016-2964-y
Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574