| Literature DB >> 27393173 |
M Tanigawa1, M Machida1,2, T Okada1.
Abstract
We addressed the strategies of mapping protein binding sites on a DNA fragment by atomic force microscopy (AFM). The protein binding site was uniquely mapped by distinguishing two termini of a linear DNA fragment. Our simple methods were found very useful to get information on transcription regulatory regions by taking advantage of long range and quick scanning by AFM.Keywords: DNA mapping; DNA-protein complex; Spl; atomic force microscopy
Year: 1997 PMID： 27393173 DOI： 10.1271/bbb.61.1751
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043