| Literature DB >> 27392220 |
Luis A Carvajal1, Ulrich Steidl2.
Abstract
Leukemia stem cells (LSCs) are resistant to current therapies used to treat chronic myeloid leukemia (CML). Abraham et al. (2016) have identified a molecular network critical for CML LSC survival and propose that simultaneously targeting two of their major transcriptional regulators, p53 and c-Myc, may facilitate their eradication.Entities:
Mesh：
Year: 2016 PMID： 27392220 DOI： 10.1016/j.stem.2016.06.005
Source DB: PubMed Journal: Cell Stem Cell ISSN： 1875-9777 Impact factor: 24.633