Literature DB >> 27392217

Burning Fat Fuels Leukemic Stem Cell Heterogeneity.

Daniel Thomas1, Ravindra Majeti2.   

Abstract

Obese leukemia patients exhibit reduced survival after chemotherapy, suggesting an important role of adipose tissue in disease progression. In this issue of Cell Stem Cell, Ye et al. (2016) reveal metabolic heterogeneity in leukemic stem cell (LSC) subpopulations and show that chemotherapy-resistant CD36+ LSCs co-opt gonadal adipose tissue to support their metabolism and survival.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27392217     DOI： 10.1016/j.stem.2016.06.014

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  6 in total

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Authors:  Alfonso E Bencomo-Alvarez; Andres J Rubio; Mayra A Gonzalez; Anna M Eiring
Journal:  Br J Haematol       Date:  2019-06-24       Impact factor: 6.998

Review 2.  The crosstalk between long non-coding RNAs and PI3K in cancer.

Authors:  Leonidas Benetatos; Evangelos Voulgaris; Georgios Vartholomatos
Journal:  Med Oncol       Date:  2017-02-07       Impact factor: 3.064

Review 3.  Role of bone marrow adipocytes in leukemia and chemotherapy challenges.

Authors:  Azin Samimi; Majid Ghanavat; Saeid Shahrabi; Shirin Azizidoost; Najmaldin Saki
Journal:  Cell Mol Life Sci       Date:  2019-02-04       Impact factor: 9.261

4.  Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19.

Authors:  Raquel Bernad; Cian J Lynch; Rocio G Urdinguio; Camille Stephan-Otto Attolini; Mario F Fraga; Manuel Serrano
Journal:  Cells       Date:  2021-04-12       Impact factor: 6.600

5.  Antineoplastic effects and mechanisms of micheliolide in acute myelogenous leukemia stem cells.

Authors:  Qing Ji; Ya-Hui Ding; Yue Sun; Yu Zhang; Hui-Er Gao; He-Nan Song; Ming Yang; Xiao-Lei Liu; Zi-Xiang Zhang; Ying-Hui Li; Ying-Dai Gao
Journal:  Oncotarget       Date:  2016-10-04

Review 6.  Emerging role of lipid metabolism alterations in Cancer stem cells.

Authors:  Mei Yi; Junjun Li; Shengnan Chen; Jing Cai; Yuanyuan Ban; Qian Peng; Ying Zhou; Zhaoyang Zeng; Shuping Peng; Xiaoling Li; Wei Xiong; Guiyuan Li; Bo Xiang
Journal:  J Exp Clin Cancer Res       Date:  2018-06-15
  6 in total

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