The first author’s name appears incorrectly in the citation. The correct citation is: Llibre JM, Raffi F, Moyle G, Behrens G, Bouee S, Reilly G, et al. (2016) An Indirect Comparison of Efficacy and Safety of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate and Abacavir/Lamivudine + Dolutegravir in Initial Therapy. PLoS ONE 11(5): e0155406. doi:10.1371/journal.pone.0155406.The Abstract is missing a sentence at the end of the “Results” subheading. The additional sentence is: In an indirect comparison, we found no statistically significant differences in efficacy, serious adverse events, drug related adverse events, drug related serious adverse events, death or selection of viral resistance between E/C/F/TDF and ABC/3TC + DTG in initial therapy.There are numerical errors in the second sentence of the first paragraph in the Results section under the subheading “Virological failure and resistance.” The correct sentence is: In GS-US-236-0102, 7% of patients on E/C/F/TDF and 10% of subjects on EFV/FTC/TDF were considered virological failures at week 144, while in SINGLE, rates were 9% and 8% for ABC/3TC + DTG and EFV/FTC/TDF, respectively.There are errors in the first two sentences of the Conclusion. The correct sentences are: With the limitation that we did not perform a systematic review we can conclude that: The indirect efficacy comparisons do not show significant differences between E/C/F/TDF and ABC/3TC + DTG. For efficacy, the difference between both regimens at week 48, 96 and 144 were small and not statistically significant; Resistance and all safety results (except for discontinuation due adverse events) also do not show significant differences between the 2 regimens.The captions for Figs 3, 4 and 5 appear incorrectly in the published article. Please see Figs 3, 4 and 5, and their correct captions here.
Fig 3
Efficacy—Indirect treatment comparison—E/C/F/TDF vs. ABC/3TC + DTG.
To the right of zero favors E/C/F/TDF (if the risk difference percentage is higher than 0, this means that the proportion is higher for E/C/F/TDF in comparison to ABC/3TC + DTG).
Fig 4
Safety—Indirect treatment comparison—E/C/F/TDF vs. ABC/3TC + DTG.
To the right of zero favors ABC/3TC + DTG (if the risk difference percentage is higher than 0, this means that the proportion of toxicity is higher for E/C/F/TDF in comparison to ABC/3TC + DTG).
Fig 5
Resistance—Indirect treatment comparison—E/C/F/TDF vs. ABC/3TC + DTG.
To the right of zero favors ABC/3TC + DTG (if the risk difference percentage is higher than 0, this means that the proportion of resistance is higher for E/C/F/TDF in comparison to ABC/3TC + DTG).
Efficacy—Indirect treatment comparison—E/C/F/TDF vs. ABC/3TC + DTG.
To the right of zero favors E/C/F/TDF (if the risk difference percentage is higher than 0, this means that the proportion is higher for E/C/F/TDF in comparison to ABC/3TC + DTG).
Safety—Indirect treatment comparison—E/C/F/TDF vs. ABC/3TC + DTG.
To the right of zero favors ABC/3TC + DTG (if the risk difference percentage is higher than 0, this means that the proportion of toxicity is higher for E/C/F/TDF in comparison to ABC/3TC + DTG).
Resistance—Indirect treatment comparison—E/C/F/TDF vs. ABC/3TC + DTG.
To the right of zero favors ABC/3TC + DTG (if the risk difference percentage is higher than 0, this means that the proportion of resistance is higher for E/C/F/TDF in comparison to ABC/3TC + DTG).
Authors: Josep M Llibre; François Raffi; Graeme Moyle; Georg Behrens; Stephane Bouee; Geraldine Reilly; Peter Borg; David Piontkowsky; Felipe Rogatto Journal: PLoS One Date: 2016-05-19 Impact factor: 3.240
Authors: Stephanie A Ruderman; Heidi M Crane; Robin M Nance; Bridget M Whitney; Barbara N Harding; Kenneth H Mayer; Richard D Moore; Joseph J Eron; Elvin Geng; William C Mathews; B Rodriguez; Amanda L Willig; Greer A Burkholder; Sara Lindström; Brian R Wood; Ann C Collier; Vani Vannappagari; Cassidy Henegar; Jean Van Wyk; Lloyd Curtis; Michael S Saag; Mari M Kitahata; Joseph A C Delaney Journal: J Acquir Immune Defic Syndr Date: 2021-03-01 Impact factor: 3.771