Literature DB >> 27390566

The Effects of Early Antibiotic Administration on Bacterial Culture Growth From Hand Abscesses.

Arianna Trionfo1, Joseph J Thoder1, Rick Tosti1.   

Abstract

BACKGROUND: Traditional management of hand abscesses consists of withholding antibiotics prior to drainage to optimize bacterial culture growth and outcome. The purpose of this study was to determine the effect of preoperative empiric antibiotics on the rate of culture growth and rate of adverse events in patients with acute hand abscesses.
METHODS: We performed a retrospective review of prospectively collected data on 88 consecutive hand abscesses that received empiric antibiotics prior to incision and drainage from 2012 to 2013 at an urban academic institution. We analyzed patient demographics, bacteriology, culture growth results, time to surgery, and frequency of adverse events.
RESULTS: The overall rate of positive culture growth was 90% (n = 79) despite running the antibiotics for a mean of 31 hours prior to debridement. Furthermore, 96% of the isolates were given a susceptible antibiotic during that time. The mean number of debridements was 1.5 per patient, but 4 re-operations were necessary for wound complications. No patients required an amputation or were upgraded to intensive care.
CONCLUSIONS: Preoperative empiric antibiotic administration does not appear to greatly reduce bacterial culture growth from hand abscesses. The adverse events are relatively few for simple abscesses treated with pre-surgical antibiotics and decompression within 24 hours.

Entities:  

Keywords:  abscess; antibiotics; culture; hand

Year:  2016        PMID: 27390566      PMCID: PMC4920536          DOI: 10.1177/1558944715627622

Source DB:  PubMed          Journal:  Hand (N Y)        ISSN: 1558-9447


  17 in total

Review 1.  Empiric antibiotics for acute infections of the hand.

Authors:  Rick Tosti; Asif M Ilyas
Journal:  J Hand Surg Am       Date:  2010-01       Impact factor: 2.230

2.  Increased prevalence of community-acquired methicillin-resistant Staphylococcus aureus in hand infections at an urban medical center.

Authors:  Ravi V Kiran; Beth McCampbell; Adam P Angeles; Richard D Montilla; Carlos Medina; Avir Mitra; John Gaughn; Julia Spears; Amit Mitra
Journal:  Plast Reconstr Surg       Date:  2006-07       Impact factor: 4.730

3.  Effect of sleep deprivation on surgeons' dexterity on laparoscopy simulator.

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Journal:  Lancet       Date:  1998-10-10       Impact factor: 79.321

4.  Conventional diagnostic challenges in periprosthetic joint infection.

Authors:  Scott R Nodzo; Thomas Bauer; Paul S Pottinger; Grant E Garrigues; Hany Bedair; Carl A Deirmengian; John Segreti; Kevin J Blount; Imran M Omar; Javad Parvizi
Journal:  J Am Acad Orthop Surg       Date:  2015-04       Impact factor: 3.020

5.  Povidone-iodine soaks for hand abscesses: a prospective randomized trial.

Authors:  Rick Tosti; Justin Iorio; John R Fowler; John Gaughan; Joseph J Thoder; Alyssa A Schaffer
Journal:  J Hand Surg Am       Date:  2014-03-11       Impact factor: 2.230

6.  Emerging multidrug resistance of methicillin-resistant Staphylococcus aureus in hand infections.

Authors:  Rick Tosti; Brian T Samuelsen; Samantha Bender; John R Fowler; John Gaughan; Alyssa A Schaffer; Asif M Ilyas
Journal:  J Bone Joint Surg Am       Date:  2014-09-17       Impact factor: 5.284

7.  Evolving incidence of MRSA in urban hand infections.

Authors:  John R Fowler; Dustin Greenhill; Alyssa A Schaffer; Joseph J Thoder; Asif M Ilyas
Journal:  Orthopedics       Date:  2013-06       Impact factor: 1.390

8.  Risk factors associated with clindamycin-resistant, methicillin-resistant Staphylococcus aureus in hand abscesses.

Authors:  Rick Tosti; Arianna Trionfo; John Gaughan; Asif M Ilyas
Journal:  J Hand Surg Am       Date:  2015-02-21       Impact factor: 2.230

9.  Community-acquired methicillin-resistant Staphylococcus aureus infections of the hand: prevalence and timeliness of treatment.

Authors:  Michael O'Malley; John Fowler; Asif M Ilyas
Journal:  J Hand Surg Am       Date:  2009-03       Impact factor: 2.230

10.  Is after-hours orthopaedic surgery associated with adverse outcomes? A prospective comparative study.

Authors:  William M Ricci; Bethany Gallagher; Angel Brandt; John Schwappach; Michael Tucker; Ross Leighton
Journal:  J Bone Joint Surg Am       Date:  2009-09       Impact factor: 5.284

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  1 in total

1.  Preoperative Antibiotics Influence Culture Yield in the Treatment of Hand, Wrist, and Forearm Infections.

Authors:  Lauren K Dutton; Katharine M Hinchcliff; Anthony L Logli; Katherine E Mallett; Gina A Suh; Marco Rizzo
Journal:  JB JS Open Access       Date:  2022-03-24
  1 in total

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