Ryota Sakurai1,2,3, Hiroyuki Suzuki3, Susumu Ogawa3, Hisashi Kawai4, Hideyo Yoshida5, Hirohiko Hirano5, Kazushige Ihara6, Shuichi Obuchi4, Yoshinori Fujiwara3. 1. Faculty of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan. 2. Research Fellow of the Japan Society for the Promotion of Science, Japan Society for the Promotion of Science, Tokyo, Japan. 3. Research Team for Social Participation and Community Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. 4. Research Team for Human Care, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. 5. Research Team for Promoting Independence of the Elderly, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. 6. Department of Public Health, Toho University School of Medicine, Tokyo, Japan.
Abstract
AIM: Understanding the risk factors for developing subjective memory complaints (SMC) could help with early screening and treatment for cognitive impairment. The aim of the present study was to explore the risk factors for developing SMC, by focusing on gait-related variables. METHODS: A total of 406 community-dwelling older adults aged 65-85 years without impending cognitive impairment participated in baseline and 1-year follow-up evaluations. A comprehensive evaluation was carried out, and included gait speed and fear of falling (FoF) assessments, and the Montreal Cognitive Assessment test. Logistic regression analyses were carried out to independently evaluate the risk factors at baseline and follow-up evaluations. RESULTS: At baseline, 45.1% of older adults had SMC. The presence of SMC at baseline was associated with being female, subjective hearing loss and FoF. Of 223 participants who did not report SMC at baseline, 48 had newly developed SMC at follow up (21.5%). The significant predictors for developing SMC were being female and FoF, but not gait speed, and were independent of depression symptoms. The Montreal Cognitive Assessment total score at baseline was a marginally significant predictor for developing SMC at follow up (P = 0.06), but a lower score in the language domain was a significant predictor in further analysis. CONCLUSIONS: FoF was a significant risk for future development of SMC, suggesting that FoF might reflect the risk of cognitive impairment at an earlier stage, or that FoF and SMC could share the same basis of anxiety for daily activities. The mechanisms and consequence of this longitudinal relationship require further study. Geriatr Gerontol Int 2017; 17: 1125-1131.
AIM: Understanding the risk factors for developing subjective memory complaints (SMC) could help with early screening and treatment for cognitive impairment. The aim of the present study was to explore the risk factors for developing SMC, by focusing on gait-related variables. METHODS: A total of 406 community-dwelling older adults aged 65-85 years without impending cognitive impairment participated in baseline and 1-year follow-up evaluations. A comprehensive evaluation was carried out, and included gait speed and fear of falling (FoF) assessments, and the Montreal Cognitive Assessment test. Logistic regression analyses were carried out to independently evaluate the risk factors at baseline and follow-up evaluations. RESULTS: At baseline, 45.1% of older adults had SMC. The presence of SMC at baseline was associated with being female, subjective hearing loss and FoF. Of 223 participants who did not report SMC at baseline, 48 had newly developed SMC at follow up (21.5%). The significant predictors for developing SMC were being female and FoF, but not gait speed, and were independent of depression symptoms. The Montreal Cognitive Assessment total score at baseline was a marginally significant predictor for developing SMC at follow up (P = 0.06), but a lower score in the language domain was a significant predictor in further analysis. CONCLUSIONS: FoF was a significant risk for future development of SMC, suggesting that FoF might reflect the risk of cognitive impairment at an earlier stage, or that FoF and SMC could share the same basis of anxiety for daily activities. The mechanisms and consequence of this longitudinal relationship require further study. Geriatr Gerontol Int 2017; 17: 1125-1131.
Authors: Roope Jaatinen; Tiina Luukkaala; Markus T Hongisto; Minna A Kujala; Maria S Nuotio Journal: Aging Clin Exp Res Date: 2022-06-21 Impact factor: 4.481
Authors: Nuria Marín-Jiménez; Carolina Cruz-León; Alejandro Perez-Bey; Julio Conde-Caveda; Alberto Grao-Cruces; Virginia A Aparicio; José Castro-Piñero; Magdalena Cuenca-García Journal: J Clin Med Date: 2022-01-10 Impact factor: 4.241