Literature DB >> 27387879

All in one: Researchers create combination drugs for diabetes and obesity.

Shraddha Chakradhar.   

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Year:  2016        PMID： 27387879     DOI： 10.1038/nm0716-694

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  6 in total

1.  Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans.

Authors:  Brian Finan; Tao Ma; Nickki Ottaway; Timo D Müller; Kirk M Habegger; Kristy M Heppner; Henriette Kirchner; Jenna Holland; Jazzminn Hembree; Christine Raver; Sarah H Lockie; David L Smiley; Vasily Gelfanov; Bin Yang; Susanna Hofmann; Dennis Bruemmer; Daniel J Drucker; Paul T Pfluger; Diego Perez-Tilve; Jaswant Gidda; Louis Vignati; Lianshan Zhang; Jonathan B Hauptman; Michele Lau; Mathieu Brecheisen; Sabine Uhles; William Riboulet; Emmanuelle Hainaut; Elena Sebokova; Karin Conde-Knape; Anish Konkar; Richard D DiMarchi; Matthias H Tschöp
Journal:  Sci Transl Med       Date:  2013-10-30       Impact factor: 17.956

2.  A new glucagon and GLP-1 co-agonist eliminates obesity in rodents.

Authors:  Jonathan W Day; Nickki Ottaway; James T Patterson; Vasily Gelfanov; David Smiley; Jas Gidda; Hannes Findeisen; Dennis Bruemmer; Daniel J Drucker; Nilika Chaudhary; Jenna Holland; Jazzminn Hembree; William Abplanalp; Erin Grant; Jennifer Ruehl; Hilary Wilson; Henriette Kirchner; Sarah Haas Lockie; Susanna Hofmann; Stephen C Woods; Ruben Nogueiras; Paul T Pfluger; Diego Perez-Tilve; Richard DiMarchi; Matthias H Tschöp
Journal:  Nat Chem Biol       Date:  2009-07-13       Impact factor: 15.040

3.  A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.

Authors:  Brian Finan; Bin Yang; Nickki Ottaway; David L Smiley; Tao Ma; Christoffer Clemmensen; Joe Chabenne; Lianshan Zhang; Kirk M Habegger; Katrin Fischer; Jonathan E Campbell; Darleen Sandoval; Randy J Seeley; Konrad Bleicher; Sabine Uhles; William Riboulet; Jürgen Funk; Cornelia Hertel; Sara Belli; Elena Sebokova; Karin Conde-Knape; Anish Konkar; Daniel J Drucker; Vasily Gelfanov; Paul T Pfluger; Timo D Müller; Diego Perez-Tilve; Richard D DiMarchi; Matthias H Tschöp
Journal:  Nat Med       Date:  2014-12-08       Impact factor: 53.440

4.  Effect of Oxyntomodulin, Glucagon, GLP-1, and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite, and Resting Energy Expenditure.

Authors:  Jonatan Ising Bagger; Jens Juul Holst; Bolette Hartmann; Birgitte Andersen; Filip Krag Knop; Tina Vilsbøll
Journal:  J Clin Endocrinol Metab       Date:  2015-10-07       Impact factor: 5.958

5.  Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations.

Authors:  Francesco Rubino; David M Nathan; Robert H Eckel; Philip R Schauer; K George M M Alberti; Paul Z Zimmet; Stefano Del Prato; Linong Ji; Shaukat M Sadikot; William H Herman; Stephanie A Amiel; Lee M Kaplan; Gaspar Taroncher-Oldenburg; David E Cummings
Journal:  Diabetes Care       Date:  2016-06       Impact factor: 19.112

6.  Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial.

Authors:  Katie Wynne; Adrian J Park; Caroline J Small; Michael Patterson; Sandra M Ellis; Kevin G Murphy; Alison M Wren; Gary S Frost; Karim Meeran; Mohammad A Ghatei; Stephen R Bloom
Journal:  Diabetes       Date:  2005-08       Impact factor: 9.461
  6 in total
  4 in total

1.  Prediction of drug combination effects with a minimal set of experiments.

Authors:  Aleksandr Ianevski; Anil K Giri; Prson Gautam; Alexander Kononov; Swapnil Potdar; Jani Saarela; Krister Wennerberg; Tero Aittokallio
Journal:  Nat Mach Intell       Date:  2019-12-09

Review 2.  Battle of GLP-1 delivery technologies.

Authors:  Minzhi Yu; Mason M Benjamin; Santhanakrishnan Srinivasan; Emily E Morin; Ekaterina I Shishatskaya; Steven P Schwendeman; Anna Schwendeman
Journal:  Adv Drug Deliv Rev       Date:  2018-07-21       Impact factor: 15.470

3.  Controlling the bioactivity of a peptide hormone in vivo by reversible self-assembly.

Authors:  Myriam M Ouberai; Ana L Gomes Dos Santos; Sonja Kinna; Shimona Madalli; David C Hornigold; David Baker; Jacqueline Naylor; Laura Sheldrake; Dominic J Corkill; John Hood; Paolo Vicini; Shahid Uddin; Steven Bishop; Paul G Varley; Mark E Welland
Journal:  Nat Commun       Date:  2017-10-18       Impact factor: 14.919

Review 4.  Ghrelin regulation of glucose metabolism.

Authors:  Anne-Laure Poher; Matthias H Tschöp; Timo D Müller
Journal:  Peptides       Date:  2018-02       Impact factor: 3.750
  4 in total

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