| Literature DB >> 27385049 |
David A Tickell1, Emma V Lampard1, John P Lowe1, Tony D James1, Steven D Bull1.
Abstract
A practically simple derivatization protocol for determining the enantiopurity of chiral diols by (1)H NMR spectroscopic analysis is described. Diols were treated with 0.5 equiv of 1,3-phenyldiboronic acid to afford mixtures of diastereomeric boronate esters whose homochiral/heterochiral ratios are an accurate reflection of the diol's enantiopurity.Entities:
Year: 2016 PMID： 27385049 DOI： 10.1021/acs.joc.6b01005
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354