Literature DB >> 27384921

Intermolecular Hydropyridylation of Unactivated Alkenes.

Xiaoshen Ma1, Seth B Herzon1,2.   

Abstract

A general method for the hydropyridylation of unactivated alkenes is described. The transformation connects metal-mediated hydrogen atom transfer to alkenes and Minisci addition reactions. The reaction proceeds under mild conditions with high site-selectivities and allows for the construction of tertiary and quaternary centers from simple alkene starting materials.

Entities:  

Year:  2016        PMID： 27384921     DOI： 10.1021/jacs.6b05271

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  20 in total

1.  Roles of Iron Complexes in Catalytic Radical Alkene Cross-Coupling: A Computational and Mechanistic Study.

Authors:  Dongyoung Kim; S M Wahidur Rahaman; Brandon Q Mercado; Rinaldo Poli; Patrick L Holland
Journal:  J Am Chem Soc       Date:  2019-04-26       Impact factor: 15.419

2.  Late-Stage C-H Alkylation of Heterocycles and 1,4-Quinones via Oxidative Homolysis of 1,4-Dihydropyridines.

Authors:  Álvaro Gutiérrez-Bonet; Camille Remeur; Jennifer K Matsui; Gary A Molander
Journal:  J Am Chem Soc       Date:  2017-08-23       Impact factor: 15.419

3.  Synthesis and Study of the Antimalarial Cardamom Peroxide.

Authors:  Xirui Hu; Pharath Lim; Rick M Fairhurst; Thomas J Maimone
Journal:  Tetrahedron       Date:  2018-03-26       Impact factor: 2.457

4.  Enantioselective Preparation of Arenes with β-Stereogenic Centers: Confronting the 1,1-Disubstituted Olefin Problem Using CuH/Pd Cooperative Catalysis.

Authors:  Zhaohong Lu; Stephen L Buchwald
Journal:  Angew Chem Int Ed Engl       Date:  2020-06-30       Impact factor: 15.336

5.  Heteroarene Phosphinylalkylation via a Catalytic, Polarity-Reversing Radical Cascade.

Authors:  J Quentin Buquoi; Jeremy M Lear; Xin Gu; David A Nagib
Journal:  ACS Catal       Date:  2019-05-06       Impact factor: 13.084

6.  γ C-H Functionalization of Amines via Triple H-Atom Transfer of a Vinyl Sulfonyl Radical Chaperone.

Authors:  James H Herbort; Taylor N Bednar; Andrew D Chen; T V RajanBabu; David A Nagib
Journal:  J Am Chem Soc       Date:  2022-07-12       Impact factor: 16.383

7.  Radical Hydroarylation of Functionalized Olefins and Mechanistic Investigation of Photocatalytic Pyridyl Radical Reactions.

Authors:  Ciaran P Seath; David B Vogt; Zihao Xu; Allyson J Boyington; Nathan T Jui
Journal:  J Am Chem Soc       Date:  2018-11-05       Impact factor: 15.419

8.  Hydroalkylation of Olefins To Form Quaternary Carbons.

Authors:  Samantha A Green; Tucker R Huffman; Ruairí O McCourt; Vincent van der Puyl; Ryan A Shenvi
Journal:  J Am Chem Soc       Date:  2019-05-03       Impact factor: 15.419

Review 9.  Radicals: Reactive Intermediates with Translational Potential.

Authors:  Ming Yan; Julian C Lo; Jacob T Edwards; Phil S Baran
Journal:  J Am Chem Soc       Date:  2016-09-26       Impact factor: 15.419

10.  Fe-Catalyzed C-C Bond Construction from Olefins via Radicals.

Authors:  Julian C Lo; Dongyoung Kim; Chung-Mao Pan; Jacob T Edwards; Yuki Yabe; Jinghan Gui; Tian Qin; Sara Gutiérrez; Jessica Giacoboni; Myles W Smith; Patrick L Holland; Phil S Baran
Journal:  J Am Chem Soc       Date:  2017-02-02       Impact factor: 15.419
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