Valdir Monteiro Pinto1,2, Mariza Vono Tancredi1, Roberto Jose de Carvalho da Silva1, Zarifa Khoury2, Cássia Maria Buchalla3. 1. Programa Estadual de DST/AIDS, Centro de Referência e Treinamento em DST/AIDS, Secretaria de Estado da Saúde, São Paulo, São Paulo, Brasil. 2. Programa Municipal de DST/AIDS, Secretaria Municipal de Saúde de São Paulo, São Paulo, São Paulo, Brasil. 3. Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, São Paulo, Brasil.
Abstract
INTRODUCTION: This study aimed to estimate the prevalence and risk factors associated with Chlamydia trachomatis (CT) infection among women with HIV in São Paulo. METHODS: This cross-sectional study included women with HIV who were receiving care from sixteen public health services in São Paulo (October 2013 to March 2014). All participants answered a questionnaire regarding their sociodemographic, behavioral, and clinical characteristics. A urine sample was tested for CT and Neisseria gonorrhoeae (NG) using the polymerase chain reaction. The chi-square test and a logistic regression model were used to test the associations with CT or NG infections. RESULTS: We evaluated 853 women and ultimately included 836 (98%) women. The mean age was 40.5 ± 0.34 years, and the prevalences of CT and NG infections were 1.8% and 0.5%, respectively. CT infection was associated with CD4+ T-cell counts of <350 cells/mm3 [adjusted odds ratio (ORadj): 24.5], age of 18-25 years (ORadj: 23.2), the non-use of condoms during the last 6 months (ORadj: 10.2), a self-reported history of a sexually transmitted infection (ORadj: 9.4), and having two or more sexual partners during the last year (ORadj: 6.1). CONCLUSIONS: Although we observed a low prevalence of CT infection among women with HIV, younger age was associated with a high risk of infection. Therefore, it may be appropriate to include screening for CT as part of the routine care for this population.
INTRODUCTION: This study aimed to estimate the prevalence and risk factors associated with Chlamydia trachomatis (CT) infection among women with HIV in São Paulo. METHODS: This cross-sectional study included women with HIV who were receiving care from sixteen public health services in São Paulo (October 2013 to March 2014). All participants answered a questionnaire regarding their sociodemographic, behavioral, and clinical characteristics. A urine sample was tested for CT and Neisseria gonorrhoeae (NG) using the polymerase chain reaction. The chi-square test and a logistic regression model were used to test the associations with CT or NG infections. RESULTS: We evaluated 853 women and ultimately included 836 (98%) women. The mean age was 40.5 ± 0.34 years, and the prevalences of CT and NG infections were 1.8% and 0.5%, respectively. CTinfection was associated with CD4+ T-cell counts of <350 cells/mm3 [adjusted odds ratio (ORadj): 24.5], age of 18-25 years (ORadj: 23.2), the non-use of condoms during the last 6 months (ORadj: 10.2), a self-reported history of a sexually transmitted infection (ORadj: 9.4), and having two or more sexual partners during the last year (ORadj: 6.1). CONCLUSIONS: Although we observed a low prevalence of CTinfection among women with HIV, younger age was associated with a high risk of infection. Therefore, it may be appropriate to include screening for CT as part of the routine care for this population.
Authors: Leonardo Miranda Dos Santos; Josiellem Damasceno de Souza; Hilary Acha Mbakwa; Akim Felipe Santos Nobre; Rodrigo Covre Vieira; Stephen Francis Ferrari; Anderson Raiol Rodrigues; Edna Aoba Yassui Ishikawa; João Farias Guerreiro; Maísa Silva de Sousa Journal: PLoS One Date: 2022-07-18 Impact factor: 3.752
Authors: Angelica E Miranda; Mariangela F Silveira; Ana Gabriela Travassos; Teresinha Tenório; Isabel Cristina Chulvis do Val; Leonor de Lannoy; Hortensio Simões de Mattos Junior; Newton Sergio de Carvalho Journal: Braz J Infect Dis Date: 2017-05-18 Impact factor: 3.257