Literature DB >> 27383638

Synthesis of Dihydropyrrolizine and Tetrahydroindolizine Scaffolds from Pyrroles by Titanocene(III) Catalysis.

Sven Hildebrandt1, Andreas Gansäuer2.   

Abstract

A synthetic approach to dihydropyrrolizine and tetrahydroindolizine scaffolds from pyrroles has been developed. The key step, a titanocene(III)-catalyzed radical arylation that proceeds by C-H functionalization is atom-economical and tolerates a large variety of functional groups. The reaction is therefore attractive for the swift assembly of functional and structural diversity.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  electron transfer; heterocyles; radicals; reaction mechanisms; titanium

Year:  2016        PMID： 27383638     DOI： 10.1002/anie.201603985

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  4 in total

1.  Asymmetric Radical Bicyclization of Allyl Azidoformates via Cobalt(II)-Based Metalloradical Catalysis.

Authors:  Huiling Jiang; Kai Lang; Hongjian Lu; Lukasz Wojtas; X Peter Zhang
Journal:  J Am Chem Soc       Date:  2017-06-29       Impact factor: 15.419

2.  Catalytic Radical Process for Enantioselective Amination of C(sp3 )-H Bonds.

Authors:  Chaoqun Li; Kai Lang; Hongjian Lu; Yang Hu; Xin Cui; Lukasz Wojtas; X Peter Zhang
Journal:  Angew Chem Int Ed Engl       Date:  2018-11-16       Impact factor: 15.336

3.  Catalytic Dibenzocyclooctene Synthesis via Cobalt(III)-Carbene Radical and ortho-Quinodimethane Intermediates.

Authors:  Colet Te Grotenhuis; Naudin van den Heuvel; Jarl Ivar van der Vlugt; Bas de Bruin
Journal:  Angew Chem Int Ed Engl       Date:  2017-12-06       Impact factor: 15.336

4.  Radical-Type Reactivity and Catalysis by Single-Electron Transfer to or from Redox-Active Ligands.

Authors:  Jarl Ivar van der Vlugt
Journal:  Chemistry       Date:  2018-11-26       Impact factor: 5.236
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.