Literature DB >> 27383145

Extending accessible chemical space for the identification of novel leads.

Jürgen Bajorath1.   

Abstract

Keywords:  Chemical space; diversity paradigm; fragment-based design; natural product-derived compounds; ultra-large chemical libraries

Mesh：

Substances：

Year:  2016        PMID： 27383145     DOI： 10.1080/17460441.2016.1210126

Source DB:  PubMed          Journal:  Expert Opin Drug Discov        ISSN： 1746-0441            Impact factor:   6.098


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  5 in total

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Authors:  Wim Dejonghe; Eugenia Russinova
Journal:  Plant Physiol       Date:  2017-03-08       Impact factor: 8.340

2.  The Brazilian compound library (BraCoLi) database: a repository of chemical and biological information for drug design.

Authors:  Gabriel Corrêa Veríssimo; Valtair Severino Dos Santos Júnior; Ingrid Ariela do Rosário de Almeida; Marina Sant'Anna Mitraud Ruas; Lukas Galuppo Coutinho; Renata Barbosa de Oliveira; Ricardo José Alves; Vinícius Gonçalves Maltarollo
Journal:  Mol Divers       Date:  2022-01-28       Impact factor: 2.943

Review 3.  Rethinking drug design in the artificial intelligence era.

Authors:  Petra Schneider; W Patrick Walters; Alleyn T Plowright; Norman Sieroka; Jennifer Listgarten; Robert A Goodnow; Jasmin Fisher; Johanna M Jansen; José S Duca; Thomas S Rush; Matthias Zentgraf; John Edward Hill; Elizabeth Krutoholow; Matthias Kohler; Jeff Blaney; Kimito Funatsu; Chris Luebkemann; Gisbert Schneider
Journal:  Nat Rev Drug Discov       Date:  2019-12-04       Impact factor: 84.694

4.  1H NMR-MS-based heterocovariance as a drug discovery tool for fishing bioactive compounds out of a complex mixture of structural analogues.

Authors:  Ulrike Grienke; Paul A Foster; Julia Zwirchmayr; Ammar Tahir; Judith M Rollinger; Emmanuel Mikros
Journal:  Sci Rep       Date:  2019-07-31       Impact factor: 4.379

Review 5.  Exploring the Multi-Target Neuroprotective Chemical Space of Benzofuran Scaffolds: A New Strategy in Drug Development for Alzheimer's Disease.

Authors:  Jaime R Cabrera-Pardo; Jorge Fuentealba; Javiera Gavilán; Daniel Cajas; José Becerra; Mariola Napiórkowska
Journal:  Front Pharmacol       Date:  2020-01-31       Impact factor: 5.810
  5 in total

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