Literature DB >> 27382290

Comparison of treatment outcomes in severe personality disorder patients with or without substance use disorders: a 36-month prospective pragmatic follow-up study.

Fernando Lana1, Carmen Sánchez-Gil1, Núria D Adroher2, Víctor Pérez3, Guillem Feixas4, Josep Martí-Bonany1, Marta Torrens3.   

Abstract

BACKGROUND: Concurrent personality disorder (PD) and substance use disorder (SUD) are common in clinical practice. However, SUD is the main criterion for study exclusion in most psychotherapeutic studies of PD. As a result, data on treatment outcomes in patients with concurrent PD/SUD are scarce.
METHODS: The study sample consisted of 51 patients diagnosed with severe PD and admitted for psychotherapeutic treatment as a part of routine mental health care. All patients were diagnosed with PD according to the Structured Clinical Interview for PD. Patients were further assessed (DSM-IV diagnostic criteria) to check for the presence of concurrent SUD, with 28 patients diagnosed with both disorders (PD-SUD). These 28 cases were then compared to the 23 patients without SUD (PD-nSUD) in terms of psychiatric hospitalizations and psychiatric emergency room (ER) visits before and during the 6-month therapeutic intervention and every 6 months thereafter for a total of 36 months.
RESULTS: The baseline clinical characteristics correspond to a sample of PD patients (78% met DSM-IV criteria for borderline PD) with poor general functioning and a high prevalence of suicide attempts and self-harm behaviors. Altogether, the five outcome variables - the proportion and the number of psychiatric inpatient admissions, the number of days hospitalized, and the proportion and the number of psychiatric ER visits - improved significantly during the treatment period, and this improvement was maintained throughout the follow-up period. Although PD-SUD patients had more psychiatric hospitalizations and ER visits than PD-nSUD patients during follow-up, the differences between these two groups remained stable over the study period indicating that the treatment was equally effective in both groups.
CONCLUSION: Specialized psychotherapy for severe PD can be effectively applied in patients with concurrent PD-SUD under usual practice conditions. These findings suggest that exclusion of patients with dual disorders from specialized treatments is unjustified.

Entities:  

Keywords:  borderline personality disorder; dual disorders; personality disorder; pragmatic clinical study; psychotherapy; substance use disorder

Year:  2016        PMID: 27382290      PMCID: PMC4922780          DOI: 10.2147/NDT.S106270

Source DB:  PubMed          Journal:  Neuropsychiatr Dis Treat        ISSN: 1176-6328            Impact factor:   2.570


  43 in total

Review 1.  A practical approach to the treatment of patients with borderline personality disorder.

Authors:  W J Livesley
Journal:  Psychiatr Clin North Am       Date:  2000-03

2.  Evaluation of intensive inpatient treatment of patients with severe personality disorders.

Authors:  G O Gabbard; L Coyne; J G Allen; H Spohn; D B Colson; M Vary
Journal:  Psychiatr Serv       Date:  2000-07       Impact factor: 3.084

3.  Practice guideline for the treatment of patients with borderline personality disorder. American Psychiatric Association.

Authors: 
Journal:  Am J Psychiatry       Date:  2001-10       Impact factor: 18.112

Review 4.  To what extent are specific psychotherapies for borderline personality disorders efficacious? A systematic review of published randomised controlled trials.

Authors:  Fernando Lana; Ma Isabel Fernández-San Martín
Journal:  Actas Esp Psiquiatr       Date:  2013-07-01       Impact factor: 1.196

5.  Comorbidity of Borderline Personality Disorder and Lifetime Substance Use Disorders in a Nationally Representative Sample.

Authors:  Ryan W Carpenter; Phillip K Wood; Timothy J Trull
Journal:  J Pers Disord       Date:  2015-04-20

6.  Generalizability of pharmacological and psychotherapy clinical trial results for borderline personality disorder to community samples.

Authors:  Nicolas Hoertel; Saioa López; Shuai Wang; Ana González-Pinto; Frédéric Limosin; Carlos Blanco
Journal:  Personal Disord       Date:  2015-01

7.  One-year follow-up of day treatment for poorly functioning patients with personality disorders.

Authors:  T Wilberg; O Urnes; S Friis; T Irion; G Pedersen; S Karterud
Journal:  Psychiatr Serv       Date:  1999-10       Impact factor: 3.084

8.  Axis II comorbidity of substance use disorders among patients referred for treatment of personality disorders.

Authors:  A E Skodol; J M Oldham; P E Gallaher
Journal:  Am J Psychiatry       Date:  1999-05       Impact factor: 18.112

9.  Substance use disorders among personality disordered patients admitted for day hospital treatment. Implications for service developments.

Authors:  Sigmund Karterud; Nina Arefjord; Nina Elin Andresen; Geir Pedersen
Journal:  Nord J Psychiatry       Date:  2009       Impact factor: 2.202

10.  Day treatment of patients with personality disorders: experiences from a Norwegian treatment research network.

Authors:  Sigmund Karterud; Geir Pedersen; Elin Bjordal; Jørgen Brabrand; Svein Friis; Oyvind Haaseth; Grete Haavaldsen; Torill Irion; Harald Leirvåg; Elin Tørum; Oyvind Urnes
Journal:  J Pers Disord       Date:  2003-06
View more
  1 in total

1.  Attachment, Mentalization, and Criterion B of the Alternative DSM-5 Model for Personality Disorders (AMPD).

Authors:  Ericka Ball Cooper; Jaime L Anderson; Carla Sharp; Hillary A Langley; Amanda Venta
Journal:  Borderline Personal Disord Emot Dysregul       Date:  2021-08-02
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.