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Literature DB >> 27381686

Antibody-targeted nanoparticles for cancer treatment.

Thomas Carter¹, Paul Mulholland^1,2, Kerry Chester¹.

Abstract

Nanoparticles (NPs) are diverse and versatile with physical properties that can be employed for use in cancer medicine. Targeting NPs using antibodies and antibody fragments could overcome some of the limitations seen with current targeted therapies. This review will discuss the role of antibody-targeted NPs in the treatment of cancer: as delivery vehicles, targeted theranostic agents and in the evolving field of cancer hyperthermia.

Entities: Disease

Keywords: antibodies; cancer treatment; clinical translation; hyperthermia; nanoparticles; targeting; theranostics

Mesh：

Substances：

Year: 2016 PMID： 27381686 DOI： 10.2217/imt.16.11

Source DB: PubMed Journal: Immunotherapy ISSN： 1750-743X Impact factor: 4.196

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Cited

12 in total

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Authors: Chenkai Mao; Michael-Joseph Gorbet; Akansha Singh; Ashish Ranjan; Steven Fiering
Journal: Int J Hyperthermia Date: 2020-12 Impact factor: 3.914

2. Nanoparticle Design Strategies for Effective Cancer Immunotherapy.

Authors: Praveena Velpurisiva; Aniket Gad; Brandon Piel; Rahul Jadia; Prakash Rai
Journal: J Biomed (Syd) Date: 2017

3. Sulfation modulates the targeting properties of hyaluronic acid to P-selectin and CD44.

Authors: Deep S Bhattacharya; Denis Svechkarev; Aishwarya Bapat; Prathamesh Patil; Michael A Hollingsworth; Aaron M Mohs
Journal: ACS Biomater Sci Eng Date: 2020-05-04

4. Drug-eluting immune checkpoint blockade antibody-nanoparticle conjugate enhances locoregional and systemic combination cancer immunotherapy through T lymphocyte targeting.

Authors: David M Francis; Margaret P Manspeaker; Paul A Archer; Lauren F Sestito; Alexander J Heiler; Alex Schudel; Susan N Thomas
Journal: Biomaterials Date: 2021-10-13 Impact factor: 12.479

Review 5. Targeting Approaches of Nanomedicines in Acute Myeloid Leukemia.

Authors: Xiao Huang; Hai Lin; Feng Huang; Yuning Xie; Ka Hong Wong; Xiaoyu Chen; Dongyue Wu; Aiping Lu; Zhijun Yang
Journal: Dose Response Date: 2019-12-11 Impact factor: 2.658

Review 6. Overcoming Hurdles in Nanoparticle Clinical Translation: The Influence of Experimental Design and Surface Modification.

Authors: Jacob W Shreffler; Jessica E Pullan; Kaitlin M Dailey; Sanku Mallik; Amanda E Brooks
Journal: Int J Mol Sci Date: 2019-11-30 Impact factor: 5.923

7. Extracellular and intracellular intermittent magnetic-fluid hyperthermia treatment of SK-Hep1 hepatocellular carcinoma cells based on magnetic nanoparticles coated with polystyrene sulfonic acid.

Authors: Bo-Wei Chen; Guo-Wei Chiu; Yun-Chi He; Chih-Yu Huang; Hao-Ting Huang; Shian-Ying Sung; Chia-Ling Hsieh; Wei-Chieh Chang; Ming-Shinn Hsu; Zung-Hang Wei; Da-Jeng Yao
Journal: PLoS One Date: 2021-02-05 Impact factor: 3.240