Literature DB >> 27381171

Epidural analgesia combined with a comprehensive physiotherapy program after Cytoreductive Surgery and HIPEC is associated with enhanced post-operative recovery and reduces intensive care unit stay: A retrospective study of 124 patients.

M Osseis1, J Weyrech2, E Gayat3, S Dagois4, R Lo Dico1, M Pocard5, C Eveno6.   

Abstract

BACKGROUND: Although Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) confers health benefits in peritoneal carcinomatosis (PC) treatment, it is associated with significant postoperative morbidity and mortality rate with increased length of hospital stay. The goal of this study is to determine whether a new comprehensive physiotherapy program including epidural loco-regional analgesia can improve the quality of care and patients recovery.
METHODS: Between 2009 and 2013, 124 patients with PC were operated for CRS and HIPEC procedures. These patients were analyzed and divided in 2 groups by means of time. No Physio group included patients operated from 2009 to 2011 (n = 57) having a thoracic patient controlled epidural analgesia (PCEA) but no preoperative physiotherapy program. The Physio group included patients operated from 2012 to 2013 (n = 67) having both a PCEA with a preoperative physiotherapy program.
RESULTS: The mortality rate was 1.6% (n = 2). The median length of stay in the intensive care unit (ICU) was lower in the Physio group, 2 days vs. 0 for No Physio group (p < 0.0001). The first time of mobilization after surgery was shorter in the Physio group (day 3 vs. 2, p = 0.0043). The overall satisfaction in the Physio group was achieved in 93% of patients, helping in decreasing fear of surgery and mobilization in 70% and 84% of cases respectively.
CONCLUSION: Our study demonstrates that a clear pre-operative information and education by a physiotherapist, associated with a PCEA-pain management significantly benefits the patient's post-operative recovery and reduces the length of stay in the ICU.
Copyright © 2016 Elsevier Ltd, BASO ~ the Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

Entities:  

Keywords:  Comprehensive physiotherapy; Enhanced recovery after surgery; Epidural loco-regional analgesia; Fast track therapy; Hyperthermic Intraperitoneal Chemotherapy; Peritoneal carcinomatosis

Mesh:

Substances:

Year:  2016        PMID: 27381171     DOI: 10.1016/j.ejso.2016.06.390

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  6 in total

1.  Impact of Enhanced Recovery After Surgery on Postoperative Outcomes for Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.

Authors:  Bradley White; Fadi Dahdaleh; Samer A Naffouje; Neerav Kothari; Jessica Berg; Wendy Wiemann; George I Salti
Journal:  Ann Surg Oncol       Date:  2021-01-19       Impact factor: 5.344

2.  Anesthesia and Pain Management for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Desmoplastic Small Round Cell Tumors in Children, Adolescents, and Young Adults.

Authors:  Doralina L Anghelescu; Christina-Lin Brown; Andrew J Murphy; Andrew M Davidoff; Paxton V Dickson; Evan S Glazer; Zachary E Stiles; Michael W Bishop; Luke Douthitt; Jeremiah L Deneve
Journal:  Ann Surg Oncol       Date:  2018-10-23       Impact factor: 5.344

Review 3.  Analgesia for Gynecologic Oncologic Surgeries: A Narrative Review.

Authors:  Kaiwal Patel; Sukhman Shergill; Nalini Vadivelu; Kanishka Rajput
Journal:  Curr Pain Headache Rep       Date:  2022-02-03

4.  Improvement of recovery parameters using patient-controlled epidural analgesia for video-assisted thoracoscopic surgery lobectomy in enhanced recovery after surgery: A prospective, randomized single center study.

Authors:  Niu Zejun; Feng Wei; Lyu Lin; Dong He; Chu Haichen
Journal:  Thorac Cancer       Date:  2018-07-27       Impact factor: 3.500

5.  A Dedicated Acute Pain Service Is Associated With Reduced Postoperative Opioid Requirements in Patients Undergoing Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy.

Authors:  Engy T Said; Jacklynn F Sztain; Wendy B Abramson; Minhthy N Meineke; Timothy J Furnish; Ulrich H Schmidt; Gerard R Manecke; Rodney A Gabriel
Journal:  Anesth Analg       Date:  2018-10       Impact factor: 5.108

Review 6.  Postoperative pain pathophysiology and treatment strategies after CRS + HIPEC for peritoneal cancer.

Authors:  Xiao Wang; Tianzuo Li
Journal:  World J Surg Oncol       Date:  2020-03-31       Impact factor: 2.754

  6 in total

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